Merlo Andrea, Cavazzuti Lorenzo, Bò Maria Chiara, Cavallieri Francesco, Bassi Maria Chiara, Damiano Benedetta, Scaltriti Sara, Fioravanti Valentina, Di Rauso Giulia, Portaro Giacomo, Valzania Franco, Lusuardi Mirco, Campanini Isabella
LAM - Motion Analysis Laboratory, Neuromotor and Rehabilitation Department, San Sebastiano Hospital, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Merlo Bioengineering, Parma, Italy.
Front Neurol. 2025 Jan 29;16:1528191. doi: 10.3389/fneur.2025.1528191. eCollection 2025.
Patients with Parkinson's disease (pwPD) and atypical parkinsonism usually complain of impaired balance. Instrumental posturography is widely used to quantitatively assess static balance in pwPD but many posturographic parameters and protocols have been suggested. We aimed to appraise the use of static posturography in pwPD and atypical parkinsonism, and identify gaps hindering its translation into clinical routine.
A systematic review on four databases. Study methodology, clinical aspects, assessment protocol, technical aspects, and transferability to clinical practice were critically appraised by a set of quality questions, scored on three levels (0, 0.5, 1). Total scores were used to assess overall studies' quality.
132 studies were included. The majority (105/132) was rated medium-quality. The domains "transferability to clinical practice" and "assessment protocol" received the lowest scores. The main flaw hindering portability to clinical settings was the lack of a stated rationale behind the choice of a specific protocol and the selection of the posturographic parameters. Missing reporting about the technical aspects employed to manage posturographic data and comprehensive instructions given to the patients further contributed to lower quality.
We provided recommendations for enhancing the clinical transferability of studies on static posturography to assess pwPD, including (1) discussing the rationale for choosing the assessment protocols and posturographic parameters, (2) detailing the inclusion criteria and select appropriate samples, and (3) reporting all the technical information to replicate the procedures and computations.
International Prospective Register of Systematic Reviews (PROSPERO) on 6th February 2024 (ID CRD42024500777), https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024500777.
帕金森病（pwPD）和非典型帕金森综合征患者通常会抱怨平衡能力受损。姿势描记仪被广泛用于定量评估pwPD患者的静态平衡，但已经提出了许多姿势描记参数和方案。我们旨在评估静态姿势描记法在pwPD和非典型帕金森综合征中的应用，并确定阻碍其转化为临床常规方法的差距。
对四个数据库进行系统综述。通过一组质量问题对研究方法、临床方面、评估方案、技术方面以及向临床实践的可转移性进行严格评估，这些问题在三个级别（0、0.5、1）上评分。总分用于评估总体研究质量。
纳入132项研究。大多数（105/1憨贰）被评为中等质量。“向临床实践的可转移性”和“评估方案”领域得分最低。阻碍向临床环境转化的主要缺陷是缺乏选择特定方案和姿势描记参数背后的明确理由。缺少关于处理姿势描记数据所采用技术方面的报告以及给予患者的全面指导进一步导致质量下降。
我们提供了增强静态姿势描记法研究临床可转移性以评估pwPD的建议，包括（1）讨论选择评估方案和姿势描记参数的理由，（2）详细说明纳入标准并选择合适的样本，以及（3）报告所有技术信息以复制程序和计算。
2024年2月6日在国际系统综述前瞻性注册库（PROSPERO）注册（ID CRD42024500777），https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024500777 。
