• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于列线图对附睾覆盖术后尿道下裂患者术后并发症的预测

Nomogram-based prediction of postoperative complications in patients with hypospadias after perididymis covering.

作者信息

Dong Jin-Ming, Gao Ya-Ke, Yang Yan-Dong, Shi Yi-Qun, Zhang Li-Na, Liu Jing, Zhao Hai-Jun, Zhao Xiao-Bo

机构信息

Department of Pediatric Surgery, Tangshan Maternal and Child Health Center, Tangshan, China.

Department of Traditional Medical Chinese Gynecology, Shijiazhuang Fourth Hospital, Shijiazhuang, China.

出版信息

Transl Pediatr. 2025 Jan 24;14(1):61-69. doi: 10.21037/tp-24-368. Epub 2025 Jan 21.

DOI:10.21037/tp-24-368
PMID:39944867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11811594/
Abstract

BACKGROUND

Hypospadias is a prevalent pediatric urological condition. Perididymis covering is often used as a surgical procedure for the treatment of hypospadias. This study aims to investigate the risk factors associated with postoperative complications following perididymis covering in the treatment of hypospadias.

METHODS

This study involved 204 patients with hypospadias who underwent perididymis cove ring at Tangshan Maternal and Child Health Hospital from May 2018 to May 2024. Patients were followed up for 1 year, with 63 experiencing complications (30.88%) and 141 not experiencing complications (69.12%). Baseline data from both groups were collected and compared. Binary logistic regression analysis was used to analyze the relationship between various factors and postoperative complications. The receiver operating characteristic (ROC) curve and the area under the curve (AUC) were utilized to evaluate the predictive value of the nomogram model for postoperative complications.

RESULTS

The complication group had a higher mean age and longer formed urethra lengths compared to the non-complication group. The types of hypospadias were categorized as intermediate, proximal, and those associated with preoperative penile curvature. The AUC for the nomogram model in the prediction of the postoperative complications was 0.909 [95% confidence interval (CI): 0.866-0.952], with a sensitivity of 0.746, a specificity of 0.929, and a Youden's index of 0.675.

CONCLUSIONS

Age, length of the formed urethra, types of hypospadias, preoperative penile curvature, and surgical methods are significantly associated with postoperative complications following perididymis covering in patients with hypospadias. These indicators can guide the formulation of clinical treatment plans to reduce the incidence of postoperative complications.

摘要

背景

尿道下裂是一种常见的小儿泌尿系统疾病。附睾覆盖术常被用作治疗尿道下裂的手术方法。本研究旨在探讨尿道下裂治疗中附睾覆盖术后并发症的相关危险因素。

方法

本研究纳入了2018年5月至2024年5月在唐山市妇幼保健院接受附睾覆盖术的204例尿道下裂患者。对患者进行1年的随访,其中63例出现并发症(30.88%),141例未出现并发症(69.12%)。收集并比较两组的基线数据。采用二元逻辑回归分析各种因素与术后并发症之间的关系。利用受试者工作特征(ROC)曲线和曲线下面积(AUC)评估列线图模型对术后并发症的预测价值。

结果

与无并发症组相比,并发症组的平均年龄更高,已形成尿道长度更长。尿道下裂类型分为中度、近端型以及与术前阴茎弯曲相关的类型。列线图模型预测术后并发症的AUC为0.909 [95%置信区间(CI):0.866 - 0.952],灵敏度为0.746,特异度为0.929,约登指数为0.675。

结论

年龄、已形成尿道长度、尿道下裂类型、术前阴茎弯曲和手术方法与尿道下裂患者附睾覆盖术后并发症显著相关。这些指标可指导临床治疗方案的制定,以降低术后并发症的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/04c6ebc4a78c/tp-14-01-61-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/22db908a7ead/tp-14-01-61-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/155318b99aa8/tp-14-01-61-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/04c6ebc4a78c/tp-14-01-61-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/22db908a7ead/tp-14-01-61-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/155318b99aa8/tp-14-01-61-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/11811594/04c6ebc4a78c/tp-14-01-61-f3.jpg

相似文献

1
Nomogram-based prediction of postoperative complications in patients with hypospadias after perididymis covering.基于列线图对附睾覆盖术后尿道下裂患者术后并发症的预测
Transl Pediatr. 2025 Jan 24;14(1):61-69. doi: 10.21037/tp-24-368. Epub 2025 Jan 21.
2
Risk factors for postoperative complications following one-stage proximal hypospadias repair involving the disconnection of the urethral plate: a retrospective study.一期近端尿道下裂修复术(涉及尿道板离断)后发生术后并发症的危险因素:一项回顾性研究。
BMC Pediatr. 2023 Oct 7;23(1):504. doi: 10.1186/s12887-023-04339-w.
3
Urological results and patient satisfaction in adolescents after surgery for proximal hypospadias in childhood.儿童期近端尿道下裂手术后青少年的泌尿外科治疗结果及患者满意度
J Pediatr Urol. 2020 Oct;16(5):660.e1-660.e8. doi: 10.1016/j.jpurol.2020.07.005. Epub 2020 Jul 15.
4
A multicenter study on surgical procedure selection and risk factor analysis of postoperative complications after TIP and Duckett hypospadias repair.一项关于 TIP 和 Duckett 尿道下裂修复术后并发症的手术方式选择和危险因素分析的多中心研究。
BMC Urol. 2022 Aug 25;22(1):131. doi: 10.1186/s12894-022-01051-2.
5
[Risk factors for the complications of primary hypospadias urethroplasty with the urethral plate reserved].
Zhonghua Nan Ke Xue. 2017 Apr;23(4):347-352.
6
Further analysis of the Glans-Urethral Meatus-Shaft (GMS) hypospadias score: correlation with postoperative complications.阴茎头-尿道外口-阴茎干(GMS)型尿道下裂评分的进一步分析:与术后并发症的相关性
J Pediatr Urol. 2015 Apr;11(2):71.e1-5. doi: 10.1016/j.jpurol.2014.11.015. Epub 2015 Feb 26.
7
Construction of nomogram based on clinical factors for the risk prediction of postoperative complications in children with choledochal cyst.基于临床因素构建预测胆总管囊肿患儿术后并发症风险的列线图。
Front Pediatr. 2024 Aug 7;12:1372514. doi: 10.3389/fped.2024.1372514. eCollection 2024.
8
[Risk factor analysis on body mass rebound after laparoscopic sleeve gastrectomy and establishment of a nomogram prediction model].腹腔镜袖状胃切除术后体重反弹的危险因素分析及列线图预测模型的建立
Zhonghua Wei Chang Wai Ke Za Zhi. 2022 Oct 25;25(10):913-920. doi: 10.3760/cma.j.cn441530-20220418-00159.
9
Single-Stage Pedicle Preputial Tube Substitution Urethroplasty with Corpora Cavernosa Augmentation Using Buccal Mucosa Graft for Primary Peno-Scrotal Hypospadias Re-pair in Adults.单阶段带蒂包皮管替代尿道成形术联合阴茎海绵体增大术,采用颊黏膜移植治疗成人原发性阴茎阴囊型尿道下裂修复术
Int Braz J Urol. 2025 Jul-Aug;51(4). doi: 10.1590/S1677-5538.IBJU.2024.0650.
10
Preoperative inflammatory markers and tumor markers in predicting lymphatic metastasis and postoperative complications in colorectal cancer: a retrospective study.术前炎症标志物和肿瘤标志物预测结直肠癌淋巴转移及术后并发症的回顾性研究
BMC Surg. 2025 Feb 18;25(1):71. doi: 10.1186/s12893-025-02795-y.

本文引用的文献

1
Increased 30-day complication rates associated with older age in children undergoing distal hypospadias repair.在接受远端尿道下裂修复术的儿童中,年龄较大与30天并发症发生率增加相关。
Int J Urol. 2024 May;31(5):576-577. doi: 10.1111/iju.15403. Epub 2024 Jan 29.
2
Hypospadias prevalence by severity and associated risk factors: A population-based active surveillance analysis.按严重程度和相关危险因素划分的尿道下裂患病率:一项基于人群的主动监测分析。
J Pediatr Urol. 2023 Dec;19(6):720.e1-720.e9. doi: 10.1016/j.jpurol.2023.08.010. Epub 2023 Aug 15.
3
Hypospadias management in children with anorectal malformation: a multidisciplinary single center experience.
肛门直肠畸形患儿的尿道下裂治疗:多学科单中心经验
Pediatr Surg Int. 2023 Jul 6;39(1):226. doi: 10.1007/s00383-023-05505-y.
4
'Waterproofing layers' for urethrocutaneous fistula repair after hypospadias surgery: evidence synthesis with systematic review and meta-analysis.尿道下裂修复术后尿道皮肤瘘修补的“防水层”:系统评价与Meta分析的证据综合
Pediatr Surg Int. 2023 Apr 3;39(1):165. doi: 10.1007/s00383-023-05405-1.
5
An insight of pathological anatomy of urethral stricture and surgical manipulations for children suffered from hypospadias.尿道下裂患儿尿道狭窄的病理解剖及手术操作要点分析
BMC Urol. 2023 Mar 18;23(1):40. doi: 10.1186/s12894-023-01209-6.
6
Age-dependent early complications of hypospadias repair: a single institutional experience.尿道下裂修复的年龄相关性早期并发症:单机构经验。
Pediatr Surg Int. 2023 Feb 11;39(1):115. doi: 10.1007/s00383-023-05388-z.
7
Missed urethral duplication associated with hypospadias, post-hypospadias repair urethral stenosis, and recurrent urinary tract infections in an adult: a case report.成人尿道重复畸形伴尿道下裂、尿道下裂修复后尿道狭窄和复发性尿路感染:病例报告。
J Med Case Rep. 2022 Sep 30;16(1):355. doi: 10.1186/s13256-022-03580-8.
8
Complication rates of proximal hypospadias: meta-analyses of four surgical repairs.近端尿道下裂的并发症发生率:四种手术修复方法的荟萃分析
J Pediatr Urol. 2022 Oct;18(5):587-597. doi: 10.1016/j.jpurol.2022.08.005. Epub 2022 Aug 17.
9
A multicenter study on surgical procedure selection and risk factor analysis of postoperative complications after TIP and Duckett hypospadias repair.一项关于 TIP 和 Duckett 尿道下裂修复术后并发症的手术方式选择和危险因素分析的多中心研究。
BMC Urol. 2022 Aug 25;22(1):131. doi: 10.1186/s12894-022-01051-2.
10
A new modified Duckett urethroplasty for repair of proximal hypospadias with severe chordee: outcomes of 133 patients.一种改良的 Duckett 尿道成形术治疗严重下弯的近端型尿道下裂:133 例患者的疗效。
BMC Urol. 2022 Mar 28;22(1):47. doi: 10.1186/s12894-022-00993-x.