Yu Dan, Su Wei, Fan Miao, Lu Lu, Wang Xinyu, Zhang Sheng, Du Qingjing, Ma Lin, Liu Ying, Yao Kaihu
Laboratory of Infection and Microbiology, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Chinese Institutes for Medical Research, Beijing, People's Republic of China.
Emerg Microbes Infect. 2025 Dec;14(1):2467773. doi: 10.1080/22221751.2025.2467773. Epub 2025 Feb 28.
Data on the clinical epidemiology of varicella in Beijing, China, remain limited. Here, we present an analysis of paediatric varicella cases from 2014 to 2023, including 10,049 cases from two children's hospitals. A gradual decline in the number of varicella cases over this period, with a marked decrease in 2020 coinciding with non-pharmaceutical interventions implemented during the COVID-19 pandemic was observed. Notably, seasonal patterns of varicella incidence weakened after 2019. Although children under four years of age accounted for the majority of cases (57.5%), the proportion of adolescents (13-18 years) increased in 2023. Our findings underscore the need for broader vaccination coverage and enhanced laboratory diagnostics to achieve effective varicella control.
中国北京水痘临床流行病学的数据仍然有限。在此，我们对2014年至2023年的儿童水痘病例进行了分析，其中包括来自两家儿童医院的10049例病例。在此期间水痘病例数逐渐下降，2020年显著减少，这与新冠疫情期间实施的非药物干预措施相吻合。值得注意的是，2019年后水痘发病率的季节性模式减弱。虽然4岁以下儿童占病例的大多数（57.5%），但2023年青少年（13 - 18岁）的比例有所增加。我们的研究结果强调了扩大疫苗接种覆盖范围和加强实验室诊断以有效控制水痘的必要性。
