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老年患者股骨远端骨折固定术后的无限制负重及术后行走能力与死亡率降低无关。

Unrestricted weightbearing and ability to achieve postoperative ambulation after distal femur fracture fixation in elderly patients is not associated with decreased mortality.

作者信息

Stockwell Erin, Urban Nathanael, Hays Matthew, McCaskey Meghan, Maseda Meghan, Mormino Matthew, Siebler Justin, Mir Hassan, Putnam Sara

机构信息

Yale University, New Haven, USA.

University of Nebraska Medical Center, Omaha, USA.

出版信息

Eur J Orthop Surg Traumatol. 2025 Feb 13;35(1):70. doi: 10.1007/s00590-025-04189-5.

Abstract

PURPOSE

The purpose of this study is to evaluate the association between 1) early postoperative mobilization on 30-day and 1-year mortality in patients ≥ 65 years who underwent fixation of distal femur fractures and 2) postoperative weightbearing instructions and early postoperative mobilization in this patient population.

METHODS

A multicentre, retrospective review of all patients ≥ 65 years of age who underwent operative fixation of a distal femur fracture between August 2012 and June 2023 at two academic level 1 trauma centres and one academic level 2 trauma centre was conducted. Univariate comparisons and binary logistic regression analyses were performed to identify factors associated with postoperative weightbearing instruction, postoperative mobilization, and mortality.

RESULTS

Three hundred and forty-seven patients were included in final analyses, with 347 patients included in the all-comer group and 274 patients included in the isolated distal femur fracture group. After adjusting for demographics and modified 5-factor frailty index (mFI-5) score, unrestricted postoperative weightbearing was associated with achievement of early postoperative mobilization in both the all-comer (p = 0.005, OR = 3.159 [95% CI 1.412-7.067]) and isolated fracture groups (p = 0.001, OR = 4.735 [95% CI 1.869-11.992]). Thirty-day mortality occurred in only 10 patients, therefore, analyses were not independently performed for this time point. After adjusting for demographics, mFI-5 score, and postoperative weightbearing instruction, postoperative mobilization was not associated with survival at one year in neither the all-comer (p = 0.281, OR = 0.589 [95% CI 0.225-1.542] nor isolated fracture groups (p = 0.432, OR = 0.664 [95% CI 0.240-1.841).

CONCLUSION

Patients with unrestricted postoperative weightbearing instructions were more likely to achieve early postoperative mobilization; however, early mobilization after fixation of distal femur fractures in patients ≥ 65 years does not appear to correlate with 1-year mortality.

摘要

目的

本研究的目的是评估1)65岁及以上接受股骨远端骨折固定术的患者术后早期活动与30天和1年死亡率之间的关联,以及2)该患者群体的术后负重指导与术后早期活动之间的关联。

方法

对2012年8月至2023年6月期间在两个一级学术创伤中心和一个二级学术创伤中心接受股骨远端骨折手术固定的所有65岁及以上患者进行多中心回顾性研究。进行单因素比较和二元逻辑回归分析,以确定与术后负重指导、术后活动和死亡率相关的因素。

结果

347例患者纳入最终分析,全人群组纳入347例患者,单纯股骨远端骨折组纳入274例患者。在调整人口统计学和改良5因素衰弱指数(mFI-5)评分后,全人群组(p = 0.005,OR = 3.159 [95% CI 1.412 - 7.067])和单纯骨折组(p = 0.001,OR = 4.735 [95% CI 1.869 - 11.992])中,术后无限制负重与术后早期活动的实现相关。仅10例患者发生30天死亡,因此,未针对该时间点单独进行分析。在调整人口统计学、mFI-5评分和术后负重指导后,全人群组(p = 0.281,OR = 0.589 [95% CI 0.225 - 1.542])和单纯骨折组(p = 0.432,OR = 0.664 [95% CI 0.240 - 1.841])中,术后活动与1年生存率均无关联。

结论

术后接受无限制负重指导的患者更有可能实现术后早期活动;然而,65岁及以上患者股骨远端骨折固定术后的早期活动似乎与1年死亡率无关。

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