Chan Jessica, Biddle Kathryn, Green Anna, Batista Craig, D'Cruz David
Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK
Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
BMJ Case Rep. 2025 Feb 13;18(2):e262905. doi: 10.1136/bcr-2024-262905.
Immunoglobulin G4-related disease (IgG4-RD) is a rare systemic fibroinflammatory disease that can affect almost any organ in the body. The most common sites of IgG4-RD include the salivary glands, orbits and lacrimal glands, pancreas, biliary tree, retroperitoneum and thyroid. Immunoglobulin G4-related lung disease (IgG4-RLD) can occur in isolation or as a component of multisystem disease. Its manifestations are heterogeneous and include lung cavitation, interstitial changes, pleural effusions and lung lesions.We describe a patient with Ig4-RLD manifesting as bronchial stenosis and left upper lobe collapse.
免疫球蛋白G4相关性疾病（IgG4-RD）是一种罕见的系统性纤维炎症性疾病，可累及身体几乎任何器官。IgG4-RD最常见的部位包括唾液腺、眼眶和泪腺、胰腺、胆管树、腹膜后和甲状腺。免疫球蛋白G4相关性肺病（IgG4-RLD）可单独发生或作为多系统疾病的一部分出现。其表现具有异质性，包括肺空洞形成、间质改变、胸腔积液和肺部病变。我们描述了一名表现为支气管狭窄和左上叶肺不张的Ig4-RLD患者。
