Baker E J, Ellam S V, Lorber A, Jones O D, Tynan M J, Maisey M N
Br Heart J. 1985 May;53(5):535-40. doi: 10.1136/hrt.53.5.535.
In 100 children with suspected left to right shunts the ratio of pulmonary to systemic flow was measured both by oximetry and first pass radionuclide angiography. The pulmonary time activity curve from the radionuclide study was analysed by the method of gamma variate fits. There was strong correlation between the two techniques; weaker correlation was found when the shunt was at atrial rather than ventricular level. This difference can be explained only by problems with the oximetric rather than the radionuclide technique. Although there are important limitations to the radionuclide method, it is the more precise and less invasive of the two and is to be preferred when the accurate measurement of left to right shunts is required.
对100名疑似存在左向右分流的儿童,通过血氧测定法和首次通过放射性核素血管造影术测量肺循环与体循环血流量的比值。放射性核素研究所得的肺循环时间-活性曲线采用伽马变量拟合方法进行分析。两种技术之间存在很强的相关性;当分流位于心房水平而非心室水平时,相关性较弱。这种差异只能用血氧测定技术而非放射性核素技术存在的问题来解释。尽管放射性核素方法存在重要局限性,但它是两种方法中更精确且侵入性更小的,在需要准确测量左向右分流时更值得选用。