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用于修复根管穿孔的冷陶瓷：一例报告

Cold Ceramic for Repairing Root Perforations: A Case Report.

作者信息

Chamani Ali, Forghani Maryam, Asadi Ghazal

机构信息

Endodontics Resident, Faculty of Dentistry Mashhad University of Medical Sciences Mashhad Iran.

Associated Professor of Endodontics, Faculty of Dentistry Mashhad University of Medical Sciences Mashhad Iran.

出版信息

Clin Case Rep. 2025 Feb 12;13(2):e70182. doi: 10.1002/ccr3.70182. eCollection 2025 Feb.

DOI:10.1002/ccr3.70182
PMID:39949583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11821458/
Abstract

Root perforation may happen pathologically or iatrogenically at any stage of endodontic treatment. Repairing a Perforation can be challenging and can negatively affect the prognosis of the treatment. The prognosis depends on various factors, including the size and site of the perforation, the presence of microorganisms, and the time lapse between injury and repair. One crucial factor is using a suitable material with favorable biocompatibility, moisture tolerance, and sealing abilities. Thus, choosing the suitable perforation sealing material can significantly affect the outcomes. Many materials have been suggested for perforation repair. However, searching for an ideal material continues, indicating the complicated nature of root perforations. In this study, three patients, two male and one female, received treatment for root perforation, each varying in the prognosis determinant factors. All cases were managed non-surgically with cold ceramic (CC) as the repairing material. After follow-up, they were clinically and radiographically examined, and all three cases revealed relatively complete healing of the tissues and no signs or symptoms of inflammation. The results obtained from the presented cases indicated CC's sealing ability, biocompatibility, moisture tolerance, and bone and periodontium regeneration, which are essential for successful perforation repair. The favorable healing of the perforation and the elimination of inflammation in every case, as well as the existing literature, support the use of CC as a suitable material for sealing perforations. However, additional clinical research is recommended to further understand CC's qualities and potential.

摘要

根管穿孔可能在牙髓治疗的任何阶段病理性或医源性地发生。修复穿孔具有挑战性，并且可能对治疗预后产生负面影响。预后取决于多种因素，包括穿孔的大小和部位、微生物的存在以及损伤与修复之间的时间间隔。一个关键因素是使用具有良好生物相容性、耐湿性和密封能力的合适材料。因此，选择合适的穿孔封闭材料会显著影响治疗结果。已经提出了许多用于穿孔修复的材料。然而，寻找理想材料的工作仍在继续，这表明根管穿孔的性质复杂。在本研究中，三名患者，两名男性和一名女性，接受了根管穿孔治疗，每个病例的预后决定因素各不相同。所有病例均采用冷陶瓷（CC）作为修复材料进行非手术治疗。随访后，对他们进行了临床和影像学检查，所有三个病例均显示组织愈合相对完全，且无炎症迹象或症状。从这些病例中获得的结果表明CC具有密封能力、生物相容性、耐湿性以及骨和牙周组织再生能力，这些对于成功修复穿孔至关重要。每个病例中穿孔的良好愈合和炎症的消除，以及现有文献，都支持将CC用作封闭穿孔的合适材料。然而，建议进行更多的临床研究以进一步了解CC的特性和潜力。

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"Effect of mid-root perforation and its repair on stress distribution and fracture resistance: a 3D finite element analysis and in vitro study".“根管中部穿孔及其修复对牙体应力分布和抗折强度的影响：三维有限元分析和体外研究”。
BMC Oral Health. 2024 Nov 4;24(1):1340. doi: 10.1186/s12903-024-05066-z.
2
Management of Maxillary Incisors With Middle-Third Root Perforation: A Case Report.上颌中切牙牙根中1/3穿孔的处理：1例病例报告
Case Rep Dent. 2024 Oct 22;2024:5957016. doi: 10.1155/2024/5957016. eCollection 2024.
3
Treatment of strip perforation using cold ceramic.
使用冷陶瓷治疗条状穿孔。
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4
Nonsurgical Endodontic Management of Large Periapical Lesion with Cold Ceramic: A Literature Review and Case Series.冷陶瓷用于大型根尖周病变的非手术牙髓治疗管理：文献综述与病例系列
Iran Endod J. 2023;18(2):113-121. doi: 10.22037/iej.v18i2.40184.
5
Present status and future directions - Managing perforations.现状与未来方向——穿孔的处理
Int Endod J. 2022 Oct;55 Suppl 4:872-891. doi: 10.1111/iej.13748. Epub 2022 Apr 28.
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Comparative evaluation of the effect of cold ceramic and MTA-Angelus on cell viability, attachment and differentiation of dental pulp stem cells and periodontal ligament fibroblasts: an in vitro study.冷瓷和 MTA-Angelus 对牙髓干细胞和牙周膜成纤维细胞活力、黏附及分化影响的比较评价：一项体外研究。
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Histopathological, histoenzymological, immunohistochemical and immunofluorescence analysis of tissue response to sealing materials after furcation perforation.对分叉穿孔后密封材料的组织反应进行组织病理学、组织酶学、免疫组织化学和免疫荧光分析。
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Effect of perforation size and furcal lesion on stress distribution in mandibular molars: a finite element analysis.穿孔大小和根分叉病变对下颌磨牙应力分布的影响：有限元分析。
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The cold ceramic material.冷陶瓷材料。
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