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1型糖尿病且有医疗补助保险的青少年自我监测血糖与持续血糖监测之间的关联

Association Between Self-Monitored Blood Glucose and Continuous Glucose Monitoring in Youth With Type 1 Diabetes and Medicaid Insurance.

作者信息

Chan Janice, Jackson Nicholas, Gonzalez Rebollar Arianna, Santana Cynthia, Perez de la Garza Giselle, Moin Tannaz, Yee Jennifer K, Everett Estelle

机构信息

Division of Endocrinology, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

Statistics Core, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

出版信息

Diabetes Care. 2025 Apr 1;48(4):632-638. doi: 10.2337/dc24-2224.

Abstract

OBJECTIVE

Youth with type 1 diabetes (T1D) and Medicaid must demonstrate they have self-monitored their blood glucose level at least four times daily to receive continuous glucose monitors (CGMs). New California Medicaid policies eliminated this requirement and, thus, CGM access has increased. This study examines whether infrequent baseline self-monitored blood glucose (SMBG) checks result in suboptimal outcomes or nonadherence with CGM use.

RESEARCH DESIGN AND METHODS

This retrospective study included youth with T1D and Medicaid who started CGM after January 2019, when newer models no longer needed calibration, at two large health care systems. Patients were stratified by data on baseline SMBG frequency (<4 vs. ≥4 checks daily) collected at the clinic visit prior to starting CGM. Differences between SMBG groups in CGM adherence and HbA1c over time were assessed by a mixed-effects linear regression model and fixed-effect interaction term. Patients were surveyed to explore individual impact of CGM on diabetes management.

RESULTS

We followed 78 youth for 6 months. CGM adherence was similar between SMBG frequency groups at 3 months (68.7% vs. 68.4%; P = 0.97) and sustained at 6 months. HbA1c values improved in both groups at 3 months, with a larger improvement in those with SMBG <4 daily checks (1.3% vs. 0.4%), and sustained at 6 months. Patient surveys (n = 35) reported high engagement with CGM and increased insulin boluses after initiation.

CONCLUSIONS

Patients using CGM demonstrated improvement in HbA1c regardless of prior SMBG. Increased engagement with CGM likely promoted increased insulin boluses. Therefore, restriction of CGM to those with SMBG ≥4 daily checks is an unnecessary barrier, excluding those who could potentially benefit the most.

摘要

目的

患有1型糖尿病(T1D)且参加医疗补助计划的青少年必须证明他们每天至少自行监测血糖水平四次,才能获得持续葡萄糖监测仪(CGM)。加利福尼亚州的新医疗补助政策取消了这一要求,因此,CGM的使用机会增加了。本研究旨在探讨不频繁的基线自我监测血糖(SMBG)检查是否会导致结果不理想或不坚持使用CGM。

研究设计与方法

这项回顾性研究纳入了在2019年1月之后开始使用CGM的患有T1D且参加医疗补助计划的青少年,当时新型号不再需要校准,研究在两个大型医疗系统中进行。患者根据开始使用CGM之前在门诊就诊时收集的基线SMBG频率数据(每天<4次与≥4次检查)进行分层。通过混合效应线性回归模型和固定效应交互项评估SMBG组之间CGM依从性和糖化血红蛋白(HbA1c)随时间的差异。对患者进行了调查,以探讨CGM对糖尿病管理的个体影响。

结果

我们对78名青少年进行了6个月的随访。在3个月时,SMBG频率组之间的CGM依从性相似(68.7%对68.4%;P = 0.97),并在6个月时保持稳定。两组的HbA1c值在3个月时均有所改善,每天SMBG检查<4次的患者改善幅度更大(1.3%对0.4%),并在6个月时保持稳定。患者调查(n = 35)显示,患者对CGM的参与度很高,并且在开始使用后胰岛素推注量增加。

结论

无论之前的SMBG情况如何,使用CGM的患者糖化血红蛋白均有所改善。对CGM的参与度增加可能促进了胰岛素推注量的增加。因此,将CGM的使用限制在每天SMBG检查≥4次的患者是不必要的障碍,排除了那些可能受益最大的患者。

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