Davoodi Marzieh, Abootalebi Seyedeh Narjes
Neonatal Research Centre, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Division of Intensive Care Unit, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Surg Case Rep. 2025 Mar;128:111011. doi: 10.1016/j.ijscr.2025.111011. Epub 2025 Feb 3.
Multisystem inflammatory syndrome in children (MIS-C) is a late-phase complication of coronavirus disease 2019 (COVID-19) featuring systemic hyperinflammation and multi-organ dysfunction.
We present the clinical features of a three-year-old girl who developed purpura fulminans and Acute Digital Necrosis and amputation while hospitalized for MIS-C.
Several MIS-C-associated complications are being reported, including arterial and venous thromboembolic events that may lead to amputation of the affected limbs.
This case emphasizes the need for to maintain a constant awareness of the possible thromboembolic MIS-C-related sequelae.
儿童多系统炎症综合征(MIS-C)是2019冠状病毒病(COVID-19)的晚期并发症,其特征为全身性高度炎症和多器官功能障碍。
我们展示了一名三岁女孩的临床特征,她在因MIS-C住院期间出现了暴发性紫癜、急性手指坏死并接受了截肢手术。
目前有多项与MIS-C相关的并发症报道,包括动脉和静脉血栓栓塞事件,这些事件可能导致受影响肢体的截肢。
该病例强调了需要持续关注与MIS-C相关的可能血栓栓塞后遗症。