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一名患有多系统炎症综合征（MIS-C）儿童的手指截肢：病例报告

Digital amputations in a child with multisystem inflammatory syndrome (MIS-C): A case report.

作者信息

Davoodi Marzieh, Abootalebi Seyedeh Narjes

机构信息

Neonatal Research Centre, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Division of Intensive Care Unit, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Int J Surg Case Rep. 2025 Mar;128:111011. doi: 10.1016/j.ijscr.2025.111011. Epub 2025 Feb 3.

DOI:10.1016/j.ijscr.2025.111011
PMID:39954546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11874814/
Abstract

INTRODUCTION AND IMPORTANCE

Multisystem inflammatory syndrome in children (MIS-C) is a late-phase complication of coronavirus disease 2019 (COVID-19) featuring systemic hyperinflammation and multi-organ dysfunction.

CASE PRESENTATION

We present the clinical features of a three-year-old girl who developed purpura fulminans and Acute Digital Necrosis and amputation while hospitalized for MIS-C.

CLINICAL DISCUSSION

Several MIS-C-associated complications are being reported, including arterial and venous thromboembolic events that may lead to amputation of the affected limbs.

CONCLUSIONS

This case emphasizes the need for to maintain a constant awareness of the possible thromboembolic MIS-C-related sequelae.

摘要

引言与重要性

儿童多系统炎症综合征（MIS-C）是2019冠状病毒病（COVID-19）的晚期并发症，其特征为全身性高度炎症和多器官功能障碍。

病例介绍

我们展示了一名三岁女孩的临床特征，她在因MIS-C住院期间出现了暴发性紫癜、急性手指坏死并接受了截肢手术。

临床讨论

目前有多项与MIS-C相关的并发症报道，包括动脉和静脉血栓栓塞事件，这些事件可能导致受影响肢体的截肢。

结论

该病例强调了需要持续关注与MIS-C相关的可能血栓栓塞后遗症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0883/11874814/c81254485a82/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0883/11874814/c81254485a82/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0883/11874814/c81254485a82/gr1.jpg

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PURPURA FULMINANS. REPORT OF A CASE SUCCESSFULLY TREATED WITH HEPARIN AND HYDROCORTISONE. REVIEW OF 50 CASES FROM THE LITERATURE.暴发性紫癜。1例肝素和氢化可的松成功治疗的病例报告。文献中50例病例的综述。
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