Smith Blake R, St-Aubin Joel, Hyer Daniel E
Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
J Appl Clin Med Phys. 2025 Apr;26(4):e70005. doi: 10.1002/acm2.70005. Epub 2025 Feb 16.
This work describes a single institution experience of commissioning a real-time target tracking and beam control system, known as comprehensive motion management, for a 1.5 T Elekta MR-Linac.
Anatomical tracking and radiation beam control were tested using the MRI Quasar motion phantom. Multiple respiratory breathing traces were modeled across a range of realistic regular and irregular breathing patterns ranging between 10 and 18 breaths per minute. Each of the breathing traces was used to characterize the anatomical position monitoring (APM) accuracy, and beam latency, and to quantify the dosimetric impact of both parameters during a respiratory-gated delivery using EBT3 film dosimetry. Additional commissioning tasks were performed to verify the dosimetric constancy during beam gating and to expand our existing quality assurance program.
It was determined that APM correctly predicted the 3D position of a dynamically moving tracking target to within 1.5 mm for 95% of the imaging frames with no deviation exceeding 2 mm. Among the breathing traces investigated, the mean latency ranged between -21.7 and 7.9 ms with 95% of all observed latencies within 188.3 ms. No discernable differences were observed in the relative profiles or cumulative output for a gated beam relative to an ungated beam with minimal dosimetric impact observed due to system latency. Measured dose profiles for all gated scenarios retained a gamma pass rate of 97% or higher for a 3%/2 mm criteria relative to a theoretical gated dose profile without latency or tracking inaccuracies.
MRI-guided target tracking and automated beam delivery control were successfully commissioned for the Elekta Unity MR-Linac. These gating features were shown to be highly accurate with an effectively small beam latency for a range of regular and irregular respiratory breathing traces.
本研究描述了在一台1.5T的医科达磁共振直线加速器(MR-Linac)上启用一种名为综合运动管理的实时目标跟踪和束流控制系统的单机构经验。
使用MRI类星体运动体模对解剖结构跟踪和辐射束流控制进行测试。针对每分钟10至18次呼吸的一系列真实规则和不规则呼吸模式,模拟了多个呼吸轨迹。每个呼吸轨迹用于表征解剖位置监测(APM)的准确性、束流延迟,并使用EBT3薄膜剂量测定法在呼吸门控放疗期间量化这两个参数的剂量学影响。还执行了其他调试任务,以验证束流门控期间的剂量学稳定性,并扩展我们现有的质量保证计划。
确定APM能在95%的成像帧中将动态移动跟踪目标的三维位置正确预测在1.5毫米以内,偏差不超过2毫米。在所研究的呼吸轨迹中,平均延迟在-21.7至7.9毫秒之间,95%的观察到的延迟在188.3毫秒以内。相对于非门控束流,门控束流的相对轮廓或累积输出未观察到明显差异,且由于系统延迟,剂量学影响最小。对于所有门控场景,相对于无延迟或跟踪不准确的理论门控剂量分布,在3%/2毫米标准下,测量的剂量分布保持97%或更高的伽马通过率。
医科达Unity MR-Linac成功启用了MRI引导的目标跟踪和自动束流输送控制。对于一系列规则和不规则呼吸轨迹,这些门控功能显示出高度准确性,束流延迟有效较小。