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[先天性膈疝。产前诊断。胸腔引流。高频通气]

[Congenital diaphragmatic hernia. Antenatal diagnosis. thoracic drainage. High frequency ventilation].

作者信息

Schmitt M, Pierre E, Prévot J, Lotte E, Droulle P

出版信息

Chir Pediatr. 1985;26(1):8-12.

PMID:3995679
Abstract

25 children with a congenital diaphragmatic hernia diagnosed in the first 24 hours of life were referred to the Clinique de Chirurgie Pédiatrique de Nancy. The total survival rate was 68%. Patients were divided into two chronologic groups. From 1979 to 1981. Of this group of 11 patients, five died: two, one week after the operation and three immediately after. From 1982 to 1984. Of those 14 patients treated, three died: two before the intervention and one three months after. Three factors explain these results: Antenatal diagnosis. It was made in 8 patients. Only one died before the operation (a 620 g polymalformated premature baby). All were in the second group. High frequency ventilation. It was made in 4 patients. All survived although one of them had a severe pulmonary hypoplasia. They were all in the second group. In 16 patients, no pleural cavity was used. These three factors act in the same way: no persistent fetal circulation. The antenatal diagnosis helps to a better neonatal care and the chances of returning to the fetal circulation are reduced. The high frequency ventilation and the absence of chest cavity drainage lessen the over inflation and barotraumatism with anoxia, acidosis, pulmonary hypertension and reversion to fetal circulation.

摘要

25例在出生后24小时内被诊断为先天性膈疝的患儿被转诊至南锡小儿外科诊所。总生存率为68%。患者被分为两个时间组。1979年至1981年。在这组11例患者中,5例死亡:2例在术后一周死亡,3例在术后即刻死亡。1982年至1984年。在接受治疗的14例患者中,3例死亡:2例在干预前死亡,1例在三个月后死亡。有三个因素可以解释这些结果:产前诊断。8例患者进行了产前诊断。只有1例在手术前死亡(一名体重620克、患有多种畸形的早产儿)。所有这些患者都在第二组。高频通气。4例患者进行了高频通气。所有患者均存活,尽管其中1例有严重的肺发育不全。他们都在第二组。16例患者未使用胸腔。这三个因素的作用方式相同:无持续性胎儿循环。产前诊断有助于更好地进行新生儿护理,减少恢复到胎儿循环的机会。高频通气和无胸腔引流可减轻过度膨胀和气压伤,以及缺氧、酸中毒、肺动脉高压和恢复到胎儿循环的情况。

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