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针刺联合整骨疗法治疗抽动秽语综合征的疗效:一项三臂随机对照试验。

Effects of acupuncture combined with bone-setting therapy to treat tourette syndrome: a three-arm randomized controlled trial.

作者信息

Jiawang Lang, Lingqing Jin, Jianchang Luo, Boxu Lang

机构信息

Department of Acupuncture and Massage, Municipal Hospital Affiliated to Medical School of Taizhou University, Taizhou 318000, China.

出版信息

J Tradit Chin Med. 2025 Feb;45(1):176-183. doi: 10.19852/j.cnki.jtcm.2025.01.017.

Abstract

OBJECTIVE

To explore the efficacy and safety of acupuncture combined with atlantoaxial joint bone-setting therapy for the treatment of Tourette syndrome.

METHODS

We randomly divided 600 patients at a ratio of 1∶1∶1 into three groups: group A (acupuncture combined with atlantoaxial joint bone setting therapy group), group B (acupuncture group), and group C (tiapride group). After two months of treatment, the Yale global tic severity scale (YGTSS) score reduction, improvement in social function impairment, clinical efficacy, and long-term efficacy in the three groups were compared.

RESULTS

After treatment, in the analysis of YGTSS score reduction, social function impairment improvement, the clinical control rate, and long-term efficacy, the results were all Group A > Group B > Group C, with a statistically significant difference ( 0.05). However, the total clinical efficacy of treatment in group A (94.9%) was not significantly different from that in group B (91.8%). Adverse reactions did not occur in groups A and B, and several adverse reactions occurred in 29% ( = 58) of the group C patients.

CONCLUSION

Compared with traditional drug therapy, acupuncture combined with atlantoaxial joint bone setting therapy has better clinical and long-term efficacy. This treatment strategy can improve the social function of children and prevent adverse reactions to drugs.

摘要

目的

探讨针刺联合寰枢关节整复疗法治疗抽动秽语综合征的疗效及安全性。

方法

将600例患者按1∶1∶1随机分为三组:A组(针刺联合寰枢关节整复疗法组)、B组(针刺组)、C组(硫必利组)。治疗2个月后,比较三组耶鲁综合抽动严重程度量表(YGTSS)评分降低情况、社会功能损害改善情况、临床疗效及远期疗效。

结果

治疗后,在YGTSS评分降低、社会功能损害改善、临床控制率及远期疗效分析中,结果均为A组>B组>C组,差异有统计学意义(P<0.05)。然而,A组治疗总有效率(94.9%)与B组(91.8%)比较差异无统计学意义。A组和B组均未发生不良反应,C组有29%(n=58)的患者出现了几种不良反应。

结论

与传统药物治疗相比,针刺联合寰枢关节整复疗法具有更好的临床疗效和远期疗效。该治疗策略可改善患儿社会功能并避免药物不良反应。

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Efficacy and Safety of Acupuncture for Tourette Syndrome in Children: A Meta-Analysis and Systematic Review.
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