Bacour Nora, Grewal Simran, Tirpan Aytug U, Theijse Rutger, Erp Olivia Van, Klautz Robert J M, Sakalihasan Natzi, Hultgren Rebecka, Grewal Nimrat
Department of Cardiothoracic Surgery, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Department of Orthopaedic Surgery, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Aorta (Stamford). 2024 Aug;12(4):86-93. doi: 10.1055/a-2524-4772. Epub 2025 Feb 17.
Acute Type A aortic dissection (ATAAD) is a life-threatening condition requiring timely surgical intervention. Despite successful surgery, postoperative outcomes are frequently suboptimal due to the high frequency of cardiovascular risk factors. This study examines baseline cardiovascular risk factors in a population of ATAAD patients in the Netherlands. Additionally, this study outlines the protocol for a randomized controlled trial, designed to improve postoperative management.Baseline data were collected from patients with ATAAD. Data were gained through the Stichting Aorta Dissectie Nederland, a Dutch association for aortic dissection patients. The data included information on cardiovascular risk factors and health-related quality of life. A survey was further conducted, to gain more insights into the ATAAD postoperative care experiences of cardiac and vascular surgeons.Among the 50 ATAAD patients in our study, we found significant cardiovascular risk factors, including smoking (36.7%), obesity (34.2%), and hypertension (51.3%). In the surgeon survey ( = 48), 84% of respondents highlighted the significance of lifestyle changes for patients, underscoring the need for individualized risk management. These findings underscore the need for tailored postoperative management programs aimed at improving patient outcomes.The results of our study highlight that ATAAD patients require comprehensive postoperative care management strategies. The ultimate goal is to enhance long-term patient outcomes and improve health-related quality of life. To address this need, the TRAIN (Targeted caRdiovAscular rIsk reductioN) Health Awareness platform seeks to implement personalized eHealth-based lifestyle interventions.
急性A型主动脉夹层(ATAAD)是一种危及生命的疾病,需要及时进行手术干预。尽管手术成功,但由于心血管危险因素的高发生率,术后结果往往不尽人意。本研究调查了荷兰ATAAD患者群体的基线心血管危险因素。此外,本研究概述了一项旨在改善术后管理的随机对照试验方案。从ATAAD患者中收集基线数据。数据通过荷兰主动脉夹层基金会(Stichting Aorta Dissectie Nederland)获得,该基金会是一个荷兰主动脉夹层患者协会。数据包括心血管危险因素和健康相关生活质量的信息。还进行了一项调查,以更深入地了解心脏和血管外科医生对ATAAD术后护理的经验。在我们研究的50例ATAAD患者中,我们发现了显著的心血管危险因素,包括吸烟(36.7%)、肥胖(34.2%)和高血压(51.3%)。在外科医生调查(n = 48)中,84%的受访者强调了生活方式改变对患者的重要性,强调了个性化风险管理的必要性。这些发现强调了需要制定针对性的术后管理计划,以改善患者的预后。我们研究的结果强调,ATAAD患者需要全面的术后护理管理策略。最终目标是提高患者的长期预后,改善健康相关生活质量。为满足这一需求,TRAIN(靶向心血管风险降低)健康意识平台寻求实施基于个性化电子健康的生活方式干预措施。