Rosen C B, Beart R W, Ilstrup D M
Dis Colon Rectum. 1985 May;28(5):305-9. doi: 10.1007/BF02560428.
A retrospective analysis was conducted of 119 consecutive patients in whom potentially curative anterior resection of invasive rectal carcinoma was performed between 1976 and 1982. Seventy-six anastomoses were stapled and 43 were hand-sewn. The distributions of tumor stage, location, histologic grade, size, and margins of resection were similar for both groups. The probability of local recurrence by two years for middle rectal tumors was 26 +/- 7 percent for the group with stapled anastomoses and 10 +/- 7 percent for those with hand-sewn anastomoses (P = 0.07, log-rank test). Local recurrence probabilities did not differ for upper rectal tumors (P = 0.14) or lower rectal tumors (P = 0.20). Anatomic considerations that encourage use of the stapler may explain our findings.
对1976年至1982年间连续119例行侵袭性直肠癌潜在根治性前切除术的患者进行回顾性分析。其中76例采用吻合器吻合，43例采用手工缝合。两组患者的肿瘤分期、位置、组织学分级、大小及切缘分布相似。直肠中部肿瘤患者，吻合器吻合组两年局部复发概率为26±7%，手工缝合组为10±7%（P = 0.07，对数秩检验）。直肠上部肿瘤（P = 0.14）和直肠下部肿瘤（P = 0.20）的局部复发概率无差异。鼓励使用吻合器的解剖学因素可能解释了我们的研究结果。
