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直肠癌低位前切除术后远切缘长度的前瞻性研究。

A prospective study of the length of the distal margin after low anterior resection for rectal cancer.

作者信息

Søndenaa K, Kjellevold K H

机构信息

Department of Surgery, Rogaland Central County Hospital, Stavanger, Norway.

出版信息

Int J Colorectal Dis. 1990 May;5(2):103-5. doi: 10.1007/BF00298480.

DOI:10.1007/BF00298480
PMID:2358734
Abstract

The length of distal margin between the lower border of the tumour and the level of division during low anterior resection may be related to the rate of local recurrence. The method of measuring the distal clearance is not usually stated in reports of the operation. The distal margin was measured prospectively in 5 different ways in 20 patients. A difference was observed between various methods of measurement of the same specimen in situ, unpinned and pinned out before and after fixation. The margin was significantly less (p less than 0.001) in unpinned compared with pinned specimens. There was poor correlation between the in situ measurement and that determined by the pathologist in both unpinned and pinned specimens. There was no significant difference before and after fixation if the specimen had been pinned but significant (p less than 0.001) shrinkage occurred with fixation when the specimen had not been pinned.

摘要

低位前切除术时肿瘤下边界与切除平面之间的远端切缘长度可能与局部复发率相关。手术报告中通常未说明测量远端切缘的方法。对20例患者的标本以5种不同方法进行了前瞻性的远端切缘测量。对同一标本在原位、未固定及固定前后展开钉住和未钉住处理后,不同测量方法间存在差异。与钉住的标本相比,未钉住标本的切缘明显更短(p<0.001)。在未钉住和钉住的标本中,原位测量与病理学家确定的测量结果之间的相关性均较差。如果标本已被钉住,固定前后无显著差异,但如果标本未被钉住,固定后会出现显著(p<0.001)收缩。

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本文引用的文献

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The gradient of mucosal surface area in the small intestine of the rat.大鼠小肠黏膜表面积的梯度
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The relationship between the extent of distal clearance and survival and local recurrence rates after curative anterior resection for carcinoma of the rectum.直肠癌根治性前切除术后远端切缘范围与生存率及局部复发率之间的关系。
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The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?直肠癌手术中的直肠系膜——盆腔复发的线索?
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Local recurrence following 'curative' surgery for large bowel cancer: II. The rectum and rectosigmoid.
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