Rammos Christos, Rassaf Tienush, Korosoglou Grigorios
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University of Duisburg-Essen, Duisburg-Essen, Deutschland.
Departments of Cardiology & Angiology, GRN Hospitals Weinheim & Eberbach, Roentgenstraße 1, 69469, Weinheim, Deutschland.
Inn Med (Heidelb). 2025 Mar;66(3):258-267. doi: 10.1007/s00108-025-01858-9. Epub 2025 Feb 17.
The endovascular treatment of the femoropopliteal segment is the most frequent revascularization option in patients with peripheral arterial occlusive disease (PAOD); however, the plain old balloon angioplasty has limitations, especially in complex and calcified lesions, and can lead to dissections and recoil. In order to improve the technical success and the efficacy of the endovascular treatment in complex, sometimes severely calcified or thrombotic lesions or also in lesions in mobile segments, a lesion preparation strategy before the actual lesion treatment is frequently applied. Lesion preparation methods include atherectomy, thrombectomy or intravascular lithotripsy. Through lesion preparation plaques and/or organized thrombi can be minimally invasively removed or calcium deposits can be even fragmented with low threshold barotrauma, without damaging the vessel wall. Subsequently, the definitive treatment of the lesion can be carried out using drug-coated balloons (DCB), bare metal stents (BMS), drug-eluting stents (DES) or a combination of these. Due to the heterogeneity of patient and lesion characteristics, no 'one fits all' strategy is so far available; however, the choice of the appropriate instruments should be carried out based on the patient and lesion characteristics present, whereby for the lesion-specific parameters the extent of the morphology and underlying pathology plays an important role.
股腘段血管腔内治疗是外周动脉闭塞性疾病(PAOD)患者最常用的血运重建方法;然而,单纯球囊血管成形术存在局限性,尤其是在处理复杂和钙化病变时,可能导致血管夹层和弹性回缩。为提高在复杂、有时严重钙化或血栓形成的病变,或活动节段病变的血管腔内治疗的技术成功率和疗效,常在实际病变治疗前采用病变预处理策略。病变预处理方法包括斑块旋切术、血栓切除术或血管内超声碎石术。通过病变预处理,斑块和/或机化血栓可被微创清除,或钙沉积物可在低阈值气压伤的情况下破碎,而不损伤血管壁。随后,可使用药物涂层球囊(DCB)、裸金属支架(BMS)、药物洗脱支架(DES)或这些方法的联合应用对病变进行最终治疗。由于患者和病变特征的异质性,目前尚无“一刀切”的策略;然而,应根据患者和现有病变特征选择合适的器械,其中对于病变特异性参数,形态学范围和潜在病理起着重要作用。