Al-Ansari Rehab Y, Al-Saidalani Raghad Hamdi, Al-Shamrani Abdulrahman Saeed, Al-Thomali Abdulrahman Eidah, Hamdan Safa, Arulanantham Zechariah Jebakumar, Woodman Alexander
Adult Hematology Unit, Internal Medicine Department, KFMMC, Dhahran, 31932, Kingdom of Saudi Arabia.
Internal Medicine Department, KFMMC, Dhahran, 31932, Kingdom of Saudi Arabia.
J Epidemiol Glob Health. 2025 Feb 17;15(1):26. doi: 10.1007/s44197-025-00363-4.
Despite the growing evidence on the thrombophilia in Saudi population along its diverse regions, there have been no studies on thrombotic events in the Eastern Province of Saudi Arabia. This single-center study aimed to investigate the prevalence of venous thromboembolism (VTE) in a hematology clinic in the Eastern Province of Saudi Arabia between January 2015 and May 2023. The objective of this study was to investigate the clinical characteristics of VTE and compare them with national data.
This is a retrospective, observational, single-center study conducted in the Eastern Province from January 2015 to May 2023. After applying the inclusion and exclusion criteria and the prevalence rate calculation an analysis of n = 170 patients was conducted to compare the epidemiological results of the current study with national data published in other provinces of Saudi Arabia. Data collected included demographics, comorbidities and location with thrombosis recurrence.
The prevalence rate of VTE in this cohort was 3.16%. Women made up 70% of the population. About 80.5% of cases were obese or overweight, 37.6% of cases had comorbidities that may increase the risk of thrombosis, and 12.9% of cases were associated with smoking. The most common site of VTE (56.5%) and the site of higher recurrence of VTE (21.8%) was the lower extremities. In addition, recurrent VTE was observed in 28.2% of cases, reflecting a significantly higher recurrence rate compared with other national studies (p = 0.001). Compared with other national statistics, the most significant risk factors for thrombosis in the Eastern Province were smoking, obesity and family history (p = 0.000). Compared with national statistics, this study demonstrated significantly higher rates of VTE in pregnancy, patients on hormonal therapy, and patients with rheumatological/autoimmune diseases (p = 0.001).
The incidence of VTE can be reduced by changing lifestyles and creating educational programs to educate people about the dangers of obesity and smoking.
尽管沙特不同地区关于血栓形成倾向的证据越来越多，但沙特阿拉伯东部省尚未有关于血栓形成事件的研究。这项单中心研究旨在调查2015年1月至2023年5月沙特阿拉伯东部省一家血液学诊所中静脉血栓栓塞（VTE）的患病率。本研究的目的是调查VTE的临床特征，并将其与全国数据进行比较。
这是一项于2015年1月至2023年5月在东部省进行的回顾性、观察性单中心研究。在应用纳入和排除标准并计算患病率后，对n = 170例患者进行了分析，以将本研究的流行病学结果与沙特阿拉伯其他省份公布的全国数据进行比较。收集的数据包括人口统计学、合并症以及血栓复发的部位。
该队列中VTE的患病率为3.16%。女性占人群的70%。约80.5%的病例肥胖或超重，37.6%的病例有可能增加血栓形成风险的合并症，12.9%的病例与吸烟有关。VTE最常见的部位（56.5%）和VTE复发率较高的部位（21.8%）是下肢。此外，28.2%的病例观察到复发性VTE，与其他全国性研究相比，复发率显著更高（p = 0.001）。与其他全国统计数据相比，东部省血栓形成最显著的风险因素是吸烟、肥胖和家族史（p = 0.000）。与全国统计数据相比，本研究显示妊娠、接受激素治疗的患者以及患有风湿性/自身免疫性疾病的患者中VTE发生率显著更高（p = 0.001）。
通过改变生活方式和制定教育计划，向人们宣传肥胖和吸烟的危害，可以降低VTE的发生率。
