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[肺腺癌子宫及附件转移:一例报告及文献复习]

[Uterine and Adnexal Metastasis of Lung Adenocarcinoma: 
A Case Report and Literature Review].

作者信息

Guo Jiangyan, Luo Pengju, Li Mei, Yuan Jing, Chen Meng, Song Shujie

机构信息

Department of Pathology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, 
Kunming 650118, China.

General Internal Department, The Third People's Hospital of Kunming, Kunming 650041, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2024 Dec 20;27(12):961-966. doi: 10.3779/j.issn.1009-3419.2024.102.40.

DOI:10.3779/j.issn.1009-3419.2024.102.40
PMID:39962852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11839497/
Abstract

Primary bronchial lung cancer, commonly known as lung cancer, is one of the malignant tumors with high morbidity and mortality in the world. In recent years, the incidence of lung cancer in women has increased, and most of them are lung adenocarcinoma. Because the early symptoms of lung cancer are occult, it is often detected when matastasis has already occurred. Endometrial and cervical metastasis is extremely rare for primary lung cancer. This article retrospectively analyzed the clinicopathological data of a patient with pulmonary microcapillary subtype adenocarcinoma with uterine and adnexal metastasis, and confirmed by morphology, immunohistochemistry and molecular detection, in order to provide references for clinical management of uterine and adnexal metastasis of lung adenocarcinoma.
.

摘要

原发性支气管肺癌,俗称肺癌,是全球发病率和死亡率较高的恶性肿瘤之一。近年来,女性肺癌发病率有所上升,且大多为肺腺癌。由于肺癌早期症状隐匿,往往在已经发生转移时才被发现。原发性肺癌发生子宫内膜和宫颈转移极为罕见。本文回顾性分析了1例发生子宫和附件转移的肺微乳头型腺癌患者的临床病理资料,并通过形态学、免疫组化及分子检测加以证实,旨在为肺腺癌子宫和附件转移的临床处理提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/11839497/3e21881fda20/zgfazz-27-12-961-img_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/11839497/6867e79054b2/zgfazz-27-12-961-img_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/11839497/3e21881fda20/zgfazz-27-12-961-img_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/11839497/6867e79054b2/zgfazz-27-12-961-img_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/11839497/3e21881fda20/zgfazz-27-12-961-img_2.jpg

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本文引用的文献

1
[Advances in the Study of Invasive Non-mucinous Adenocarcinoma 
with Different Pathological Subtypes].[不同病理亚型侵袭性非黏液腺癌的研究进展]
Zhongguo Fei Ai Za Zhi. 2023 Jan 20;26(1):22-30. doi: 10.3779/j.issn.1009-3419.2022.102.51.
2
Cancer statistics, 2023.癌症统计数据,2023 年。
CA Cancer J Clin. 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763.
3
Epidermal growth factor receptor-mutated lung adenocarcinoma diagnosed from endometrial polyp metastasis: A case report and literature review.经子宫内膜息肉转移诊断的表皮生长因子受体突变型肺腺癌:一例报告及文献复习
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4
Next-generation sequencing assisted diagnosis of cervical metastasis in EGFR-mutated lung adenocarcinoma: A case report.下一代测序辅助诊断 EGFR 突变型肺腺癌的宫颈转移:一例报告。
Thorac Cancer. 2021 Oct;12(19):2622-2627. doi: 10.1111/1759-7714.14143. Epub 2021 Sep 9.
5
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.外泌体中四种基因作为鉴定肺腺癌和肺鳞癌生物标志物的应用。
Oncol Lett. 2021 Apr;21(4):249. doi: 10.3892/ol.2021.12510. Epub 2021 Feb 3.
6
Would extirpative pelvic surgery improve survival in gynecological metastases of lung cancer? Case report and review of the literature.盆腔根治性手术能否提高肺癌妇科转移患者的生存率?病例报告及文献综述。
Int Cancer Conf J. 2020 Sep 13;10(1):24-30. doi: 10.1007/s13691-020-00441-3. eCollection 2021 Jan.
7
Lung adenocarcinoma with EGFR gene mutation metastatic to the uterine cervix: A case report.伴有EGFR基因突变的肺腺癌转移至子宫颈:一例报告
Medicine (Baltimore). 2020 Oct 16;99(42):e22636. doi: 10.1097/MD.0000000000022636.
8
Isolated uterine metastasis from a lung adenocarcinoma.肺腺癌的孤立性子宫转移。
BMJ Case Rep. 2019 Dec 8;12(12):e232487. doi: 10.1136/bcr-2019-232487.
9
Female genital tract metastasis of lung adenocarcinoma with EGFR mutations: Report of two cases.伴有表皮生长因子受体(EGFR)突变的肺腺癌女性生殖道转移:两例报告
World J Clin Cases. 2019 Jun 26;7(12):1515-1521. doi: 10.12998/wjcc.v7.i12.1515.
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In Vivo. 2019 Jul-Aug;33(4):1369-1372. doi: 10.21873/invivo.11613.