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腹部创伤手术后再次剖腹手术的适应证、危险因素及临床结局

Indications, risk factors, and clinical outcomes of relaparotomy after abdominal trauma surgery.

作者信息

Demir Mehmet Bahadır, Celik Suleyman Utku, Kaymak Sahin

机构信息

Department of General Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Türkiye.

出版信息

Ulus Travma Acil Cerrahi Derg. 2025 Feb;31(2):119-124. doi: 10.14744/tjtes.2024.32736.

Abstract

BACKGROUND

Relaparotomy following abdominal trauma surgery is a critical intervention associated with significant morbidity and mortality. However, data on relaparotomy in trauma patients remain limited. This study aimed to evaluate the impact of relaparotomy-related factors on prognosis in patients undergoing relaparotomy after abdominal trauma surgery.

METHODS

This retrospective study analyzed adult patients who underwent relaparotomy following abdominal trauma surgery at a single center between December 2016 and December 2022. Demographic characteristics, trauma-related features, and perioperative clinical findings were recorded. Statistical analyses were conducted to identify factors associated with in-hospital mortality.

RESULTS

Among 300 patients who underwent abdominal trauma surgery, 106 (35.3%) required relaparotomy. The in-hospital mortality rate was 9.4%. Major indications for relaparotomy included hemorrhage control, hemodynamic instability, and intestinal leaks. Factors significantly associated with increased mortality included age ≥50 years (p=0.020), female sex (p=0.031), blunt trauma (p=0.020), multiple relaparotomies (p=0.023), active hemorrhage during relaparotomy (p<0.001), and fresh frozen plasma transfusion (p=0.046). Additionally, non-survivors demonstrated significantly lower blood pressure (p<0.001) and higher heart rates (p<0.001). They also presented with decreased levels of hemoglobin (p=0.015), platelet counts (p=0.001), and albumin (p<0.001), along with elevated international normalized ratio (INR) (p<0.001) and lactate levels (p<0.001).

CONCLUSION

This study highlights key factors associated with mortality in patients undergoing relaparotomy after abdominal trauma surgery. Early recognition and optimization of risk factors, along with the management of active hemorrhage, careful monitoring of vital signs and laboratory parameters, and special attention to high-risk groups such as older patients and those with blunt trauma, may improve outcomes in this vulnerable population.

摘要

背景

腹部创伤手术后再次剖腹手术是一项关键干预措施,与显著的发病率和死亡率相关。然而,关于创伤患者再次剖腹手术的数据仍然有限。本研究旨在评估再次剖腹手术相关因素对腹部创伤手术后接受再次剖腹手术患者预后的影响。

方法

这项回顾性研究分析了2016年12月至2022年12月期间在单一中心接受腹部创伤手术后再次剖腹手术的成年患者。记录了人口统计学特征、创伤相关特征和围手术期临床发现。进行统计分析以确定与院内死亡率相关的因素。

结果

在300例接受腹部创伤手术的患者中,106例(35.3%)需要再次剖腹手术。院内死亡率为9.4%。再次剖腹手术的主要指征包括控制出血、血流动力学不稳定和肠漏。与死亡率增加显著相关的因素包括年龄≥50岁(p=0.020)、女性(p=0.031)、钝性创伤(p=0.020)、多次再次剖腹手术(p=0.023)、再次剖腹手术期间活动性出血(p<0.001)和新鲜冰冻血浆输注(p=0.046)。此外,非幸存者的血压显著降低(p<0.001),心率较高(p<0.001)。他们还表现出血红蛋白水平降低(p=0.015)、血小板计数降低(p=0.001)和白蛋白降低(p<0.001),同时国际标准化比值(INR)升高(p<0.001)和乳酸水平升高(p<0.001)。

结论

本研究强调了腹部创伤手术后接受再次剖腹手术患者死亡率相关的关键因素。早期识别和优化危险因素,以及处理活动性出血、仔细监测生命体征和实验室参数,特别关注老年患者和钝性创伤患者等高风险人群,可能会改善这一脆弱人群的预后。

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