Ookura Ryusuke, Usuki Noriaki, Miki Yukio
Department of Diagnostic and Interventional Radiology, Japan Community Healthcare Organization Osaka Hospital, 4-2-78, Fukushima, Fukushima-ku, Osaka, 553-0003, Japan.
Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3, Asahi-Machi, Abeno-Ku, Osaka, 545-8585, Japan.
Jpn J Radiol. 2025 Feb 18. doi: 10.1007/s11604-025-01752-2.
To investigate the relationship between the computed tomography (CT) value of the adrenal glands in the arterial phase of dynamic contrast-enhanced CT and the severity of acute pancreatitis.
We measured the maximum CT values of the adrenal glands on the arterial phase of dynamic contrast-enhanced CT of patients with acute pancreatitis and compared them with those of the non-pancreatitis group. Moreover, we evaluated the correlations between the adrenal CT values and maximum C-reactive protein (CRPmax) and CRP/albumin ratio (CAR) in the clinical courses.
In this retrospective study, a total of 68 patients was included. The maximum CT value of the adrenal glands of pancreatitis group was significantly higher than that of the control group (p < 0.001). Significant fair correlations were observed between the adrenal CT value and CRPmax (r = 0.483, p < 0.001) or CAR (r = 0.450, p < 0.001). The cut-off value of the adrenal CT values was determined as 180.5 Hounsfield unit.
In cases of acute pancreatitis, the maximum CT value of the adrenal gland in the arterial phase of dynamic contrast-enhanced CT was significantly higher than in non-pancreatitis controls, and the intensity of the contrast enhancement correlated with the CRPmax and CAR during the subsequent course of pancreatitis. This finding may assist in predicting the severity of acute pancreatitis.
探讨动态对比增强CT动脉期肾上腺的CT值与急性胰腺炎严重程度之间的关系。
我们测量了急性胰腺炎患者动态对比增强CT动脉期肾上腺的最大CT值，并将其与非胰腺炎组进行比较。此外，我们评估了肾上腺CT值与临床病程中最大C反应蛋白（CRPmax）和CRP/白蛋白比值（CAR）之间的相关性。
在这项回顾性研究中，共纳入68例患者。胰腺炎组肾上腺的最大CT值显著高于对照组（p < 0.001）。肾上腺CT值与CRPmax（r = 0.483，p < 0.001）或CAR（r = 0.450，p < 0.001）之间存在显著的中度相关性。肾上腺CT值的截断值确定为180.5亨氏单位。
在急性胰腺炎病例中，动态对比增强CT动脉期肾上腺的最大CT值显著高于非胰腺炎对照组，且对比增强强度与胰腺炎后续病程中的CRPmax和CAR相关。这一发现可能有助于预测急性胰腺炎的严重程度。
