Connell Kathryn A, Davis Billie S, Kahn Jeremy M
University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania.
Department of Critical Care Medicine, University of Pittsburgh School of Medicine, and.
Ann Am Thorac Soc. 2025 May;22(5):742-748. doi: 10.1513/AnnalsATS.202406-603OC.
Continuity of nursing care is highly valued in the intensive care unit (ICU), but its impact on patient outcomes remains unclear. To investigate the relationship between nurse continuity and mortality among ICU patients. We performed a retrospective cohort study using electronic health records from 38 ICUs across 18 hospitals between 2018 and 2020. Cumulative nurse continuity was defined at the shift level as the proportion of 12-hour shifts in which the patient received care from a nurse who had previously provided care to them, up to and including the present shift. Employing a landmark analysis framework, we used logistic regression to assess the relationship between in-hospital mortality and cumulative nurse continuity at each shift, adjusting for potential confounders. The study included 47,564 ICU patients. In-hospital mortality was 10.4%. Average cumulative nurse continuity increased from 10.2% at shift 3 to 34.2% at shift 14. In the regression models, increasing cumulative nurse continuity was associated with a modest but statistically significant increase in mortality in some but not all shifts. The results were robust to sensitivity analyses, including limiting the cohort to patients receiving mechanical ventilation, excluding patients admitted during the COVID-19 pandemic, using different measures of continuity, and treating continuity as a time-varying covariate using proportional hazards regression. Nurse continuity was not associated with lower mortality and may lead to increased mortality in some settings. Further research is needed to understand the mechanisms underlying the association between nurse continuity and ICU outcomes.
在重症监护病房(ICU)中,护理的连续性备受重视,但其对患者预后的影响仍不明确。为了研究ICU患者中护士连续性与死亡率之间的关系,我们进行了一项回顾性队列研究,使用了2018年至2020年期间18家医院38个ICU的电子健康记录。累积护士连续性在班次层面被定义为患者接受曾为其提供过护理的护士护理的12小时班次的比例,直至并包括当前班次。采用标志性分析框架,我们使用逻辑回归来评估每个班次住院死亡率与累积护士连续性之间的关系,并对潜在混杂因素进行调整。该研究纳入了47,564名ICU患者。住院死亡率为10.4%。平均累积护士连续性从第3个班次的10.2%增加到第14个班次的34.2%。在回归模型中,累积护士连续性的增加在某些但并非所有班次中与死亡率适度但具有统计学意义的增加相关。这些结果在敏感性分析中是稳健的,包括将队列限制为接受机械通气的患者、排除在COVID-19大流行期间入院的患者、使用不同的连续性测量方法以及使用比例风险回归将连续性作为随时间变化的协变量进行处理。护士连续性与较低的死亡率无关,在某些情况下可能导致死亡率增加。需要进一步研究以了解护士连续性与ICU预后之间关联的潜在机制。