Fujimoto Takuya, Maekawa Yoko, Hori Shinichi, Oguro Atsushi, Hori Atsushi, Fujita Ikuo, Sakurai Yoshinori, Tanaka Hiroki, Ito Tatsuya, Yahiro Shunsuke, Sakuma Toshiko, Suzuki Minoru
Department of Orthopaedic Surgery, Hyogo Cancer Center, Akashi, 673-8558, Japan.
National Hospital Organization Kobe Medical Center, Breast Surgical Oncology, Kobe, 654-0155, Japan.
Appl Radiat Isot. 2025 May;219:111715. doi: 10.1016/j.apradiso.2025.111715. Epub 2025 Feb 10.
Here described for the first time is the efficacy of p-boronophenylalanine (BPA)-based BNCT in the clinical treatment of metastatic breast cancer. The patient was diagnosed with left axillary lymph node metastasis from breast cancer with comorbidity of neuropathy. Although several treatment strategies for suppressing the progression of the cancer were unavailing, BPA-based BNCT impeded the progression. This clinical case suggests the applicability of this new method of treatment to not only metastatic but also primary breast cancer.