丙烷磺内酯预处理对小鼠Friend病毒白血病发生的影响。
Effect of propane sultone pretreatment on Friend virus leukemogenesis in mice.
作者信息
Raikow R B, OKunewick J P, Buffo M J, Kociban D L
出版信息
Experientia. 1985 May 15;41(5):664-6. doi: 10.1007/BF02007709.
PMID:3996543
Abstract
Propane sultone (PS) injected i.p. 24 or more hours before Friend leukemia virus increased the incidence of lymphoma in SJL/J mice and at a higher dose increased the incidence of erythroleukemia in B10SJF1 mice. PS at the same time also decreased hematopoietic stem cell clonogenicity.
摘要
在给SJL/J小鼠注射弗氏白血病病毒前24小时或更长时间腹腔注射丙烷磺内酯（PS），可增加淋巴瘤的发病率，而在B10SJF1小鼠中，较高剂量的PS可增加红白血病的发病率。同时，PS也会降低造血干细胞的克隆形成能力。
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