Mazur Łukasz, Balwierz Radosław, Michalak Krzysztof, Michalak Wojciech, Jasińska-Balwierz Agata, Shanaida Mariia, Biernat Paweł, Baj Tomasz, Jasicka-Misiak Izabela
Institute of Chemistry, University of Opole, Opole, Poland.
Institute of Medical Sciences, University of Opole, Opole, Poland.
Planta Med. 2025 Apr;91(4):173-188. doi: 10.1055/a-2535-2003. Epub 2025 Feb 18.
Green tea catechins are bioactive polyphenolic compounds that possess a number of biological activities and potential health benefits. This review will focus on discussing the effects of green tea catechins, with a particular emphasis on clinical studies that evaluate their anticancer potential. Epigallocatechin gallate (EGCG), either as a stand-alone treatment or in conjunction with conventional anticancer therapies, represents a promising alternative strategy for the management of leukaemia. This review was based on a search of the scientific sources indexed in the databases PubMed and Scopus using the following keywords: '', 'tea catechins', 'anticancer', 'antioxidant', 'hematological cancer', and 'leukaemia' in combination. A deeper comprehension of the multifaceted mechanisms and findings of research could facilitate the development of novel strategies and the integration of green tea catechins into clinical practice, thus enhancing treatment outcomes for patients with leukaemia.
绿茶儿茶素是具有多种生物活性和潜在健康益处的生物活性多酚化合物。本综述将重点讨论绿茶儿茶素的作用，尤其着重于评估其抗癌潜力的临床研究。表没食子儿茶素没食子酸酯（EGCG），无论是作为单独治疗还是与传统抗癌疗法联合使用，都代表了一种有前景的白血病治疗替代策略。本综述基于使用以下关键词组合在PubMed和Scopus数据库中索引的科学文献来源进行检索：“”、“茶儿茶素”、“抗癌”、“抗氧化剂”、“血液系统癌症”和“白血病”。对研究的多方面机制和结果有更深入的理解，可能有助于开发新策略并将绿茶儿茶素纳入临床实践，从而提高白血病患者的治疗效果。
