Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.
Laboratory of Pathophysiology and Biochemistry of Nutrition, Department of Basic and Experimental Nutrition, Institute of Nutrition, Rio de Janeiro State University/UERJ, Rio de Janeiro 20550-013, Brazil.
Molecules. 2024 Sep 26;29(19):4575. doi: 10.3390/molecules29194575.
Green tea is the second most consumed beverage following water, and the health benefits provided by its consumption have been well established from research in recent decades. The main bioactive compounds found in all -based teas are catechins, which have been reported to have antioxidant, anticancer, anti-inflammatory, and immunomodulatory properties. Although most of the health benefits are well established, studies show that the intact catechins as found in tea are poorly absorbed in the digestive tract. These compounds are degraded and undergo ring fission by the gut microbiota, increasing their absorption. In this review, we gather knowledge of the health benefits of green tea catechins and their metabolites, with a particular emphasis on the immunomodulatory effects in a cancer microenvironment scenario.
绿茶是仅次于水的第二大消费饮品，近年来的研究已经充分证实了其饮用带来的健康益处。所有茶类中发现的主要生物活性化合物是儿茶素，据报道它们具有抗氧化、抗癌、抗炎和免疫调节特性。尽管大多数健康益处已经得到充分证实，但研究表明，在消化道中，完整的儿茶素吸收不良。这些化合物在肠道微生物群的作用下被降解并发生环裂，从而增加了它们的吸收。在这篇综述中，我们收集了绿茶儿茶素及其代谢物的健康益处知识，特别强调了它们在癌症微环境中的免疫调节作用。
