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大鼠力竭运动后血浆、肝脏和肌肉中谷胱甘肽状态的变化。

Changes in the glutathione status of plasma, liver and muscle following exhaustive exercise in rats.

作者信息

Lew H, Pyke S, Quintanilha A

出版信息

FEBS Lett. 1985 Jun 17;185(2):262-6. doi: 10.1016/0014-5793(85)80919-4.

DOI:10.1016/0014-5793(85)80919-4
PMID:3996604
Abstract

Our results show that following physical exercise to exhaustion, the levels of reduced glutathione are increased in the plasma, but decreased in both the liver and skeletal muscle of rats. Levels of glutathione disulfide are increased in all 3 tissues. Our results are consistent with a mechanism in which the liver may be dumping reduced glutathione into the plasma in an attempt to deliver it to those tissues that need it the most: in this case, skeletal muscle.

摘要

我们的研究结果表明,在进行力竭性体育锻炼后,大鼠血浆中还原型谷胱甘肽水平升高,但肝脏和骨骼肌中的还原型谷胱甘肽水平均降低。所有三种组织中的二硫化谷胱甘肽水平均升高。我们的研究结果与一种机制相符,即肝脏可能会将还原型谷胱甘肽释放到血浆中,试图将其输送到最需要它的组织:在这种情况下,即骨骼肌。

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