Trindade Bruno Lovaglio Cançado, Coelho Isadora Brito, Magalhães Larissa Lima, Crepaldi Letícia Arriel, Man Fu Frederico Moreira, Da Glória Luiza Machado Ribeiro
Cornea Department, Instituto de Olhos Ciências Médicas, Belo Horizonte, Brazil.
Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, Brazil.
Clin Ophthalmol. 2025 Feb 13;19:527-534. doi: 10.2147/OPTH.S507490. eCollection 2025.
To analyze indications safety and potential complications of cosmetic therapeutic corneal keratopigmentation to treat disfiguring aspect of opaque corneas.
Eight eyes of 8 consecutive patients were enrolled in therapeutic corneal keratopigmentation. Surgery was performed using manual technique, and a two-plane corneal dissection was performed. In the deeper pocket, brown pigment was injected to mimic iris color. In the more superficial and smaller pocket, black pigment was used to simulate pupillary opening.
Seven out of 8 eyes had significant improvements in cosmesis after surgery. One patient did not have a major improvement due to significant superficial corneal neovascularization. In two eyes, there was pigment fading in the postoperative period, but no additional surgeries were performed. No complications were noted in any of the patients.
Therapeutic corneal keratopigmentation can lead to a significant change in ocular appearance and may improve self-esteem and overall life quality. Pigment fading and corneal neovascularization can be a potential problem. Careful patient selection and counseling are important to avoid patients seeking unachievable results.
分析用于治疗角膜混浊所致容貌毁损的美容性治疗性角膜色素沉着术的适应证、安全性及潜在并发症。
连续8例患者的8只眼纳入治疗性角膜色素沉着术。采用手工技术进行手术，进行双平面角膜剥离。在较深的腔隙中注入棕色色素以模拟虹膜颜色。在较浅且较小的腔隙中，使用黑色色素模拟瞳孔开口。
8只眼中有7只眼术后容貌有显著改善。1例患者因角膜表面明显新生血管形成而无明显改善。2只眼在术后出现色素褪色，但未进行额外手术。所有患者均未出现并发症。
治疗性角膜色素沉着术可导致眼部外观显著改变，并可能提高自尊和整体生活质量。色素褪色和角膜新生血管形成可能是一个潜在问题。仔细选择患者并进行咨询对于避免患者追求无法实现的结果很重要。
