Department of Ophthalmology, GSVM Medical College, Kanpur, Uttar Pradesh, India.
AIIMS, Rishikesh, Uttarakhand, India.
Int Ophthalmol. 2023 Aug;43(8):2787-2794. doi: 10.1007/s10792-023-02700-7. Epub 2023 May 25.
The aim of this study was to improve cosmesis in patients with corneal opacity (CO) using newer organic micronized pigments.
Settings: Tertiary Care eye center, Design: Retrospective study.
Patients with unsightly corneal scars not suitable for keratoplasty, eccentric corneal opacity not requiring keratoplasty, or lenticular opacity/anterior or posterior capsular opacities in non-seeing eyes. Micronized organic pigment was used for keratopigmentation by the intrastromal pocket technique (ISPT) in deep corneal opacities and lenticular opacities, whereas the intrastromal needle puncture technique (ISNT) was used in superficial opacities or corneoiridic scars. The records of 463 patients were reviewed and analyzed for the duration of the past 7 years.
Two hundred and ninety-three (63.2%) patients underwent ISNT, eight underwent combined technique, and the rest underwent ISPT. The postoperative follow-up period showed more watering and redness in the needle puncture technique (p > 0.001), which resolved in 70.4% of patients by the end of 4 weeks. Repeat procedures were required in 5.3% of the patients with ISNT. The patient's satisfaction grading showed excellent levels in 375 (80.9%) patients, 45 (9.7%) had good satisfaction levels, and the rest had average satisfaction levels.
Intrastromal keratopigmentation is a boon for unsightly corneal scars and gives respite to the patients from the social stigma.
本研究旨在使用新型有机微粉颜料改善角膜混浊（CO）患者的美容效果。
地点：三级眼科中心，设计：回顾性研究。
角膜瘢痕不适合进行角膜移植术、偏心性角膜混浊不需要进行角膜移植术、或无视力眼的晶状体混浊/前或后囊混浊的患者。微粉有机颜料通过间质袋技术（ISPT）用于深层角膜混浊和晶状体混浊的角膜色素沉着术，而间质针穿刺技术（ISNT）用于浅层混浊或角膜虹膜瘢痕。回顾性分析了过去 7 年中 463 例患者的记录并进行了分析。
293 例（63.2%）患者接受 ISNT 治疗，8 例患者接受联合技术治疗，其余患者接受 ISPT 治疗。术后随访期显示，针穿刺技术的眼部分泌物和红肿更多（p>0.001），4 周后 70.4%的患者症状缓解。ISNT 治疗的 5.3%患者需要重复手术。患者满意度分级显示 375 例（80.9%）患者满意度优秀，45 例（9.7%）患者满意度良好，其余患者满意度一般。
间质角膜色素沉着术是改善不美观角膜瘢痕的一种方法，可减轻患者的社会耻辱感。
