Mishra Pravash Ranjan, Purkait Suvendu, Manekar Aditya Arvind, Tripathy Bikasha Bihary
Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
J Indian Assoc Pediatr Surg. 2025 Jan-Feb;30(1):66-69. doi: 10.4103/jiaps.jiaps_182_24. Epub 2025 Jan 2.
Untreated cryptorchid testes are in risk of intratubular germ cell neoplasia and subsequently may give rise to invasive germ cell tumors.
Tissue samples were obtained from patients undergoing orchidectomy or orchiopexy and were subjected to routine histopathological and immunohistochemical examinations.
Forty-three patients were enrolled in this study out of which 30 samples were collected. The mean age of patients was 9.16 years. One case (6.7%) showed positivity of the germ cell neoplasia with anto placental alkaline phosphatase and Anto CD-117 positive. Other histopathological findings such as fibrocollagenous tissue and Leydig cell hyperplasia were reported.
Early surgical management is of importance for a better outcome in cases of undescended testes.
未治疗的隐睾存在发生管内生殖细胞瘤的风险，随后可能引发侵袭性生殖细胞肿瘤。
从接受睾丸切除术或睾丸固定术的患者获取组织样本，并进行常规组织病理学和免疫组织化学检查。
本研究纳入43例患者，其中收集了30份样本。患者的平均年龄为9.16岁。1例（6.7%）显示生殖细胞瘤对胎盘碱性磷酸酶呈阳性，且抗CD - 117阳性。还报告了其他组织病理学发现，如纤维胶原组织和莱迪希细胞增生。
早期手术治疗对于隐睾病例获得更好的预后很重要。
