Zancopè Nicola, De Monte Francesca, Simeone Erica, Giannone Angelo, Lombardi Riccardo, Mele Alessandro, Zorz Alessandra, Di Paola Alessandro, Causin Francesco, Paiusco Marta
Department of Physics and Astronomy "Galileo Galilei", University of Padova, Padua, Italy.
Medical Physics Department, Veneto Institute of Oncology IOV - IRCCS, Via Gattamelata n. 64, Padua, 35128, Italy.
Sci Rep. 2025 Feb 19;15(1):6091. doi: 10.1038/s41598-025-90509-y.
This study aims to validate the Size Specific Dose Estimate (SSDE) provided by a modern Computed Tomography (CT) scanner and investigate its correlation with effective dose (E). SSDE is a size-specific dosimetric index addressing the limitations of the Computed Tomography Dose Index (CTDI). A set of 60 CT scans of anthropomorphic phantoms, including pediatric and obese models, were acquired and analyzed. SSDE values from the CT scanner were compared with those obtained through an independent Python-based calculation and Radimetrics, a dose monitor software. While the independent calculation and the one with Radimetrics were consistently in agreement, a systematic underestimation by the scanner up to 10% was seen, particularly in chest and abdominal exams. The underestimation, however, remained within the acceptable limits set by AAPM guidelines. Furthermore, a correlation between SSDE and effective dose was identified, suggesting SSDE's potential for more accurate, size-specific radiation dose and risk assessments. These findings highlight the importance of SSDE in enhancing patient-specific dose management, though further validation using patient data is needed to confirm its clinical applicability.
本研究旨在验证现代计算机断层扫描（CT）扫描仪提供的特定尺寸剂量估计（SSDE），并研究其与有效剂量（E）的相关性。SSDE是一种针对计算机断层扫描剂量指数（CTDI）局限性的特定尺寸剂量学指标。采集并分析了一组60例包含儿童和肥胖模型的人体模型CT扫描图像。将CT扫描仪的SSDE值与通过基于Python的独立计算以及剂量监测软件Radimetrics获得的值进行比较。虽然独立计算结果与使用Radimetrics的计算结果始终一致，但发现扫描仪存在高达10%的系统性低估，尤其是在胸部和腹部检查中。不过，这种低估仍在AAPM指南设定的可接受范围内。此外，还确定了SSDE与有效剂量之间的相关性，这表明SSDE在进行更准确的特定尺寸辐射剂量和风险评估方面具有潜力。这些发现凸显了SSDE在加强患者特定剂量管理方面的重要性，不过需要使用患者数据进行进一步验证以确认其临床适用性。
