Ngo Nguyen L, Asfour Maher, Tran Kayla, Cheung Gordon, Mai Thinh
Medicine, Kansas City University, Joplin, USA.
Medicine, Kansas City University, Kansas City, USA.
Cureus. 2025 Jan 20;17(1):e77721. doi: 10.7759/cureus.77721. eCollection 2025 Jan.
Transcranial magnetic stimulation (TMS), a non-invasive tool that uses magnetic fields to stimulate specific regions within the brain, has emerged as a versatile treatment modality in both research and clinical settings. While its utilization in psychiatry for treatment-resistant depression is well established, TMS is increasingly gaining traction for its use in diverse neurological conditions, including idiopathic facial nerve palsy, post-stroke rehabilitation, autism spectrum disorder, and hereditary ataxia. Through its ability to trigger neuronal plasticity and potentiate synaptic transmission, it is able to provide significant therapeutic potential. This paper seeks to explore and add to the rising research in treating idiopathic facial nerve palsy with the use of peripheral TMS. A 26-year-old woman with no prior history of facial palsy or related conditions presented with acute-onset left-sided facial paralysis upon awakening, following a strenuous hiking trip the previous day. Based on the modified House-Brackmann scale, she was determined to have grade V facial paralysis (severe facial weakness with barely perceptible motion). After 10 treatments over the course of two weeks, the patient's facial paralysis improved to grade III (obvious, moderate facial weakness, complete eye closure with maximal effort, and good forehead movement). At one-week post-TMS treatment, the patient reported full recovery to all facial expressions and no adverse effects were noted. This case report aims to show the effectiveness of utilizing TMS as a treatment option for idiopathic facial nerve palsy.
经颅磁刺激(TMS)是一种利用磁场刺激脑内特定区域的非侵入性工具,已成为研究和临床环境中一种多功能的治疗方式。虽然其在精神病学中用于治疗难治性抑郁症已得到充分证实,但TMS在多种神经系统疾病中的应用越来越受到关注,包括特发性面神经麻痹、中风后康复、自闭症谱系障碍和遗传性共济失调。通过其触发神经元可塑性和增强突触传递的能力,它具有显著的治疗潜力。本文旨在探索并补充关于使用外周TMS治疗特发性面神经麻痹的不断增加的研究。一名26岁女性,既往无面神经麻痹或相关疾病史,在前一天进行剧烈徒步旅行后醒来时出现急性左侧面瘫。根据改良的House-Brackmann量表,她被判定为V级面瘫(严重面部无力,几乎没有可察觉的运动)。在两周内进行10次治疗后,患者的面瘫改善为III级(明显的中度面部无力,用力时可完全闭眼,额头运动良好)。在TMS治疗后一周,患者报告所有面部表情完全恢复,未观察到不良反应。本病例报告旨在展示利用TMS作为特发性面神经麻痹治疗选择的有效性。