Laranne J, Rimpiläinen I, Karma P, Eskola H, Häkkinen V, Laippala P
Department of Otorhinolaryngology, School of Medicine, University of Tampere, Finland.
Eur Arch Otorhinolaryngol. 1995;252(6):344-7. doi: 10.1007/BF00178274.
The aim of this study was to examine the neuronographic findings of electrical and transcranial magnetic stimulation of the facial nerve and to compare their ability to predict clinical recovery from idiopathic facial nerve palsy (Bell's palsy). Eighty-six patients were examined clinically and neurophysiologically immediately on presentation to Tampere University Hospital. Electroneuronography (ENoG) and transcranial magnetic stimulation (TMS) were performed 1-6 times for each patient. The time interval between each examination varied from 2 to 7 days. Seventy-eight patients were followed for a median period of 13 months after the onset of palsy. Facial nerve function was graded according to the House-Brackmann grading system. Relative amplitude differences of ENoG and TMS during the acute phase were then correlated with clinical outcome. Statistical analysis of the results showed that a TMS response elicitable during the first 5 days of the palsy was correlatable with a good prognosis. ENoG results correlated with clinical outcome at a later time from onset of symptoms. TMS was well tolerated and no adverse effects were seen. These results indicate that TMS is a useful method for the early prediction of outcome in patients with Bell's palsy.
本研究的目的是检查面神经电刺激和经颅磁刺激的神经电图结果,并比较它们预测特发性面神经麻痹(贝尔麻痹)临床恢复情况的能力。86例患者在就诊于坦佩雷大学医院时立即接受了临床和神经生理学检查。对每位患者进行了1 - 6次神经电图(ENoG)和经颅磁刺激(TMS)检查。每次检查之间的时间间隔为2至7天。78例患者在面瘫发作后中位随访13个月。根据House - Brackmann分级系统对面神经功能进行分级。然后将急性期ENoG和TMS的相对振幅差异与临床结果进行关联。结果的统计分析表明,在面瘫发作的前5天内可引出的TMS反应与良好预后相关。ENoG结果在症状发作后的较晚时间与临床结果相关。TMS耐受性良好,未观察到不良反应。这些结果表明,TMS是早期预测贝尔麻痹患者预后的一种有用方法。