Ahuja Navdeep, Pathania Monika, Mohan Latika, Mittal Sunita, Bhardwaj Praag, Dhar Minakshi
Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Physiology, All India Institute of Medical Sciences, Bilaspur, Bilaspur, IND.
Cureus. 2025 Jan 20;17(1):e77717. doi: 10.7759/cureus.77717. eCollection 2025 Jan.
Background Hypertension [blood pressure (BP) >130/80 mmHg] contributes significantly to cardiovascular morbidity and mortality. Lifestyle modifications, including mindfulness-based practices like Yoga, meditation, and relaxation techniques, have emerged as promising adjuncts to pharmacotherapy. This study aimed to explore the acute effects of Yoga Nidra (YN) on BP in essential hypertension and the potential mechanisms of the effect of YN on BP, in the form of changes in heart rate variability (HRV) components. Methods A total of 32 hypertensive individuals (mean age: 43 ±0.54 years; 22 males, 10 females) were enrolled at the Lifestyle Disease Clinic. Patients were provided regular consultation and pharmacotherapy. BP and HRV were assessed before and after a 16-minute YN session. HRV parameters included time and frequency domain measures. Statistical analysis included linear regression to study the relationship of components of HRV with those of the changes in BP. Results Following YN intervention, there was a significant reduction in both systolic BP (SBP) (7 mmHg) and diastolic BP (DBP) (6 mmHg). HRV analysis revealed significant increases. Regression analysis showed changes in SBP having significant coefficients. Conclusions A single session of YN reduced the systolic and diastolic BP and increased HRV parameters. Regression analyses showed that the reduction in BP can be explained by an increase in HRV parameters. Thus, this study demonstrates the positive effect of YN as an intervention for essential hypertension and also the potential mechanisms behind it, which can be explained by the Neurovisceral Integration Model.
背景 高血压（血压>130/80 mmHg）是心血管疾病发病和死亡的重要原因。包括瑜伽、冥想和放松技巧等基于正念的生活方式改变，已成为药物治疗有前景的辅助手段。本研究旨在探讨瑜伽休息术（YN）对原发性高血压患者血压的急性影响，以及YN通过心率变异性（HRV）成分变化影响血压的潜在机制。方法 在生活方式疾病诊所招募了32名高血压患者（平均年龄：43±0.54岁；男性22名，女性10名）。为患者提供定期咨询和药物治疗。在16分钟的YN疗程前后评估血压和HRV。HRV参数包括时域和频域测量。统计分析包括线性回归，以研究HRV成分与血压变化成分之间的关系。结果 经过YN干预后，收缩压（SBP）显著降低（7 mmHg），舒张压（DBP）显著降低（6 mmHg）。HRV分析显示有显著增加。回归分析表明SBP的变化具有显著系数。结论 单次YN疗程可降低收缩压和舒张压，并增加HRV参数。回归分析表明，血压降低可由HRV参数增加来解释。因此，本研究证明了YN作为原发性高血压干预措施的积极作用及其背后的潜在机制，这可以用神经内脏整合模型来解释。
