卡介苗两疗程序贯诱导治疗高危非肌层浸润性膀胱癌患者的长期疗效 - Suppr

Long-term efficacy of two sequential induction courses of Bacillus Calmette-Guérin in patients with high-risk non-muscle-invasive bladder cancer.

作者信息

Seo Ho Kyung, Jung Eui Hyun, Song Geehyun

机构信息

Department of Urology, Center for Urologic Cancer, Hospital/Division of Tumor Immunology, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, Republic of Korea.

出版信息

Transl Androl Urol. 2025 Jan 31;14(1):4-7. doi: 10.21037/tau-24-466. Epub 2025 Jan 22.

DOI:10.21037/tau-24-466

PMID:39974797

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11833530/

Abstract

摘要

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Response to 2 Induction Courses of Bacillus Calmette-Guèrin Therapy Among Patients With High-Risk Non-Muscle-Invasive Bladder Cancer: 5-year Follow-Up of a Phase 2 Clinical Trial.高危非肌层浸润性膀胱癌患者接受卡介苗治疗的 2 个诱导疗程的反应：2 期临床试验的 5 年随访。

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Theories behind Bacillus Calmette-Guérin failure in high-risk non-muscle-invasive bladder cancer and update on current management.高危非肌层浸润性膀胱癌中卡介苗治疗失败的理论及当前治疗进展

Cancer Pathog Ther. 2023 Nov 29;2(2):74-80. doi: 10.1016/j.cpt.2023.11.004. eCollection 2024 Apr.

JAMA Oncol. 2024 Apr 1;10(4):522-525. doi: 10.1001/jamaoncol.2023.6804.

IL-15 Superagonist NAI in BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer.白细胞介素-15 超级激动剂 NAI 在卡介苗无应答性非肌肉浸润性膀胱癌中的作用。

NEJM Evid. 2023 Jan;2(1):EVIDoa2200167. doi: 10.1056/EVIDoa2200167. Epub 2022 Nov 10.

Phase 2 Trial of Atezolizumab in Bacillus Calmette-Guérin-unresponsive High-risk Non-muscle-invasive Bladder Cancer: SWOG S1605.atezolizumab 在卡介苗无应答高危非肌肉浸润性膀胱癌中的 2 期临床试验：SWOG S1605。

Eur Urol. 2023 Dec;84(6):536-544. doi: 10.1016/j.eururo.2023.08.004. Epub 2023 Aug 16.

Efficacy of Different Bacillus of Calmette-Guérin (BCG) Strains on Recurrence Rates among Intermediate/High-Risk Non-Muscle Invasive Bladder Cancers (NMIBCs): Single-Arm Study Systematic Review, Cumulative and Network Meta-Analysis.不同卡介苗（BCG）菌株对中/高危非肌层浸润性膀胱癌（NMIBC）复发率的疗效：单臂研究的系统评价、累积和网状荟萃分析

Cancers (Basel). 2023 Mar 23;15(7):1937. doi: 10.3390/cancers15071937.

Non-maintenance intravesical Bacillus Calmette-Guérin induction therapy with eight doses in patients with high- or highest-risk non-muscle invasive bladder cancer: a retrospective non-randomized comparative study.高风险或极高风险非肌层浸润性膀胱癌患者行 8 剂卡介苗非维持膀胱内诱导治疗：一项回顾性非随机对照研究。

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Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial.纳武拉非尼基因导管治疗卡介苗无应答性非肌肉浸润性膀胱癌：一项单臂、开放标签、重复剂量临床试验。

Lancet Oncol. 2021 Jan;22(1):107-117. doi: 10.1016/S1470-2045(20)30540-4. Epub 2020 Nov 27.

Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer.训练免疫作为膀胱癌卡介苗免疫治疗的分子机制。

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Eur Urol. 2020 Nov;78(5):690-698. doi: 10.1016/j.eururo.2020.04.066. Epub 2020 May 20.

KEYNOTE-676: Phase III study of BCG and pembrolizumab for persistent/recurrent high-risk NMIBC.KEYNOTE-676：卡介苗和帕博利珠单抗用于持续性/复发性高危非肌层浸润性膀胱癌的 III 期研究。

Future Oncol. 2020 Apr;16(10):507-516. doi: 10.2217/fon-2019-0817. Epub 2020 Mar 12.

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Long-term efficacy of two sequential induction courses of Bacillus Calmette-Guérin in patients with high-risk non-muscle-invasive bladder cancer.

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