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放疗中基于深度学习的危及器官自动分割临床应用的审计。

Auditing the clinical usage of deep-learning based organ-at-risk auto-segmentation in radiotherapy.

作者信息

Mason Josh, Doherty Jack, Robinson Sarah, de la Bastide Meagan, Miskell Jack, McLauchlan Ruth

机构信息

Department of Radiobiology and Radiation Physics, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road W6 8RF London, UK.

出版信息

Phys Imaging Radiat Oncol. 2025 Jan 30;33:100716. doi: 10.1016/j.phro.2025.100716. eCollection 2025 Jan.

DOI:10.1016/j.phro.2025.100716
PMID:39981522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11840498/
Abstract

For 18 months following clinical introduction of deep-learning auto-segmentation (DLAS), an audit of organ at risk (OAR) contour editing was performed, including 1255 patients from a single institution and the majority of tumour sites. Mean surface-Dice similarity coefficient increased from 0.87 to 0.97, the number of unedited OARs increased from 21.5 % to 40 %. The audit identified changes in editing corresponding to vendor model changes, adaption of local contouring practice and reduced editing in areas of no clinical significance. The audit allowed assessment of the level and frequency of editing and identification of outlier cases.

摘要

在深度学习自动分割(DLAS)临床应用后的18个月里,对危及器官(OAR)轮廓编辑进行了一次审核,涵盖了来自单一机构的1255名患者以及大多数肿瘤部位。平均表面骰子相似系数从0.87提高到0.97,未编辑的OAR数量从21.5%增加到40%。审核发现编辑方面的变化与供应商模型的变化、局部轮廓绘制实践的调整以及临床无意义区域编辑的减少相对应。该审核有助于评估编辑的水平和频率,并识别异常病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faf/11840498/cac35f48a800/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faf/11840498/cac35f48a800/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faf/11840498/cac35f48a800/gr1a.jpg

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本文引用的文献

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An audit of the impact of the introduction of a commercial artificial intelligence-driven auto-contouring tool into a radiotherapy department.
Br J Radiol. 2025 Mar 1;98(1167):375-382. doi: 10.1093/bjr/tqae255.
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A joint ESTRO and AAPM guideline for development, clinical validation and reporting of artificial intelligence models in radiation therapy.《ESTRO 和 AAPM 联合指南:放疗人工智能模型的开发、临床验证和报告》
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A geometry and dose-volume based performance monitoring of artificial intelligence models in radiotherapy treatment planning for prostate cancer.基于几何和剂量体积的人工智能模型在前列腺癌放射治疗计划中的性能监测。
Phys Imaging Radiat Oncol. 2023 Sep 23;28:100494. doi: 10.1016/j.phro.2023.100494. eCollection 2023 Oct.
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Monitoring Variations in the Use of Automated Contouring Software.监测自动化轮廓勾画软件使用情况的变化。
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Automated contouring and statistical process control for plan quality in a breast clinical trial.一项乳腺癌临床试验中计划质量的自动轮廓描绘与统计过程控制
Phys Imaging Radiat Oncol. 2023 Aug 23;28:100486. doi: 10.1016/j.phro.2023.100486. eCollection 2023 Oct.
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Automated Contouring and Planning in Radiation Therapy: What Is 'Clinically Acceptable'?放射治疗中的自动轮廓勾画与计划:何为“临床可接受”?
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Artificial Intelligence for Radiotherapy Auto-Contouring: Current Use, Perceptions of and Barriers to Implementation.人工智能在放射治疗自动勾画中的应用:现状、认知与实施障碍。
Clin Oncol (R Coll Radiol). 2023 Apr;35(4):219-226. doi: 10.1016/j.clon.2023.01.014. Epub 2023 Jan 23.
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Real-world analysis of manual editing of deep learning contouring in the thorax region.胸部区域深度学习轮廓手动编辑的真实世界分析
Phys Imaging Radiat Oncol. 2022 May 14;22:104-110. doi: 10.1016/j.phro.2022.04.008. eCollection 2022 Apr.
9
Clinically Applicable Segmentation of Head and Neck Anatomy for Radiotherapy: Deep Learning Algorithm Development and Validation Study.临床可应用的头颈部解剖结构勾画:放射治疗深度学习算法的开发与验证研究。
J Med Internet Res. 2021 Jul 12;23(7):e26151. doi: 10.2196/26151.
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Phys Imaging Radiat Oncol. 2020 Oct 14;16:54-60. doi: 10.1016/j.phro.2020.10.001. eCollection 2020 Oct.