Meisel Meishar, Berkowitz Eran, Schwalb Avi, Tiosano Beatrice
Department of Ophthalmology, Hillel Yaffe Medical Center, Hadera, Israel.
The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Case Rep Ophthalmol. 2025 Jan 30;16(1):68-73. doi: 10.1159/000543219. eCollection 2025 Jan-Dec.
Herein, we report on the option and clinical advantage of the Preserflo MicroShunt insertion into the posterior chamber ciliary sulcus in a patient with advanced pseudoexfoliation glaucoma at a high risk of corneal decompensation.
We describe a 64-year-old advanced pseudoexfoliation glaucoma patient who despite maximal tolerated medical therapy and two failed glaucoma surgeries, still suffered from uncontrolled intraocular pressure (IOP) of 36 mm Hg in his left eye. The patient underwent the implantation of the Preserflo MicroShunt. The shunt was placed nasally into an area of unscarred conjunctiva, with the anterior part of the shunt inserted into the ciliary sulcus. Postoperatively, the patient's IOP dropped to 6 mm Hg on the first day and stabilized at 11 mm Hg at the 6-month mark. An elevated, posteriorly located bleb was observed, and the patient no longer required additional topical medications. Endothelial cell (EC) count remained stable with no signs of corneal edema. The patient did not experience any serious postoperative complications.
Implantation of the Preserflo MicroShunt into the ciliary sulcus appears to be a viable option for patients at high risk of corneal decompensation, hence, offering effective IOP control while minimizing EC loss. Further studies with larger patient groups are warranted to better evaluate the safety and efficacy of this technique.
在此,我们报告了在一名角膜失代偿风险高的晚期假性剥脱性青光眼患者中,将Preserflo微型分流器植入后房睫状沟的选择及临床优势。
我们描述了一名64岁的晚期假性剥脱性青光眼患者,尽管接受了最大耐受量的药物治疗且两次青光眼手术均失败,但他的左眼眼压仍高达36毫米汞柱且未得到控制。该患者接受了Preserflo微型分流器植入术。分流器经鼻放置于未瘢痕化的结膜区域,分流器前部插入睫状沟。术后,患者眼压在第一天降至6毫米汞柱,并在6个月时稳定在11毫米汞柱。观察到一个隆起的、位于后方的滤过泡,患者不再需要额外的局部用药。内皮细胞(EC)计数保持稳定,无角膜水肿迹象。患者未出现任何严重的术后并发症。
将Preserflo微型分流器植入睫状沟对于角膜失代偿风险高的患者似乎是一种可行的选择,因此,在有效控制眼压的同时可使内皮细胞损失最小化。有必要对更大的患者群体进行进一步研究,以更好地评估该技术的安全性和有效性。