一种测定人外周血单个核细胞抗体依赖性细胞毒性（ADCC）的方法。
A method for determination of antibody-dependent cellular cytotoxicity (ADCC) of human peripheral mononuclear cells.
作者信息
Wisecarver J, Bechtold T, Collins M, Davis J, Lipscomb H, Sonnabend J, Purtilo D T
出版信息
J Immunol Methods. 1985 May 23;79(2):277-82. doi: 10.1016/0022-1759(85)90107-3.
A method is described for measuring antibody-dependent cellular cytotoxicity (ADCC) of mononuclear cells from human peripheral blood using an established murine cell line and commercially prepared antisera. The test utilizes a standard 51Cr release technique. The ADCC activity of mononuclear cells obtained from 10 healthy human volunteers was measured at 4 different effector: target cell ratios. A linear relationship between %51Cr release (ADCC) and the number of effector cells was observed.
描述了一种使用已建立的鼠细胞系和商业制备的抗血清来测量人外周血单个核细胞的抗体依赖性细胞毒性（ADCC）的方法。该测试采用标准的51Cr释放技术。在4种不同的效应细胞：靶细胞比例下，测量了从10名健康人类志愿者获得的单个核细胞的ADCC活性。观察到51Cr释放百分比（ADCC）与效应细胞数量之间存在线性关系。
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