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台湾地区降低环境细颗粒物水平对新生儿后婴儿存活的健康益处。

Health benefits of a reduction in ambient fine particulate matter levels for post-neonatal infant survival in Taiwan.

作者信息

Chen Chih-Cheng, Tsai Shang-Shyue, Yeh Chien-Ning, Yang Chun-Yuh

机构信息

Department of pediatrics, College of Medicine, Kaohsiung Chang-Gung Memorial Hospital, Chang-Gung University, Kaohsiung, Taiwan.

Department of Healthcare Administration, I-Shou University, Kaohsiung, Taiwan.

出版信息

J Toxicol Environ Health A. 2025;88(13):536-545. doi: 10.1080/15287394.2025.2469079. Epub 2025 Feb 22.

Abstract

Infants' and children's health is particularly susceptible to exposure to various environmental contaminant insults as their immune systems are immature and daily activities may present differing patterns of exposure. Although some studies noted an association between long-term exposure to ambient fine particulate matter (PM) and increased infant mortality frequency, few investigations examined the relationship between reduced exposure to PM and changes in infant mortality rates. Therefore, this study was conducted to determine whether diminished levels of PM in Taiwan improved post-neonatal infant health. Avoidable premature post-neonatal infant mortality was employed as an indicator of health impact. A mean value was calculated for annual PM levels across Taiwan for the years 2006, 2015, and 2023. Using these averages and following WHO methodology, differences in the number of post-neonatal infant deaths attributed to ambient PM exposure were determined. PM concentrations fell markedly throughout Taiwan over the 20-year study period. In conjunction with this decline, a lowered health burden was noted, which was represented as a fall in post-neonatal infant deaths (14.8% in 2006 to 10.3% in 2023). Reduction in annual levels of PM to 10 µg/m was associated with a decrease in the total burden of post-neonatal infant mortality occurrence, with a 5.58-9.31% decline in PM-related deaths during that period. Evidence indicates that exposure to PM air pollution poses a significant burden to Taiwan children's health. Our findings indicate that the potential benefits to children's health need to be given importance when considering improving air quality policies.

摘要

婴儿和儿童的健康特别容易受到各种环境污染物侵害的影响,因为他们的免疫系统尚未发育成熟,日常活动可能呈现出不同的接触模式。尽管一些研究指出长期接触环境细颗粒物(PM)与婴儿死亡率上升之间存在关联,但很少有调查研究接触PM减少与婴儿死亡率变化之间的关系。因此,本研究旨在确定台湾地区PM水平的降低是否改善了新生儿后期婴儿的健康状况。将可避免的新生儿后期婴儿过早死亡用作健康影响的指标。计算了2006年、2015年和2023年台湾地区全年PM水平的平均值。利用这些平均值并遵循世界卫生组织的方法,确定了归因于环境PM暴露的新生儿后期婴儿死亡数量的差异。在为期20年的研究期间,台湾地区的PM浓度显著下降。随着这种下降,观察到健康负担有所减轻,表现为新生儿后期婴儿死亡人数的减少(从2006年的14.8%降至2023年的10.3%)。将年度PM水平降至10 µg/m³与新生儿后期婴儿死亡总负担的降低相关,在此期间与PM相关的死亡人数下降了5.58 - 9.31%。有证据表明,接触PM空气污染给台湾儿童的健康带来了重大负担。我们的研究结果表明,在考虑改善空气质量政策时,需要重视对儿童健康的潜在益处。

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