Yang Linlei, Shen Zhenhui, Luo Xiangying, Li Rongping, Li Rongchun
Kunming (Edible Fungi) Enterprise Technology Center, Yunnan (Rare Edible Fungi) Enterprise Technology Center, Yunnan Junshijie Biotechnology Co. Ltd., Kunming 650200, Yunnan, China.
Zhang Jinsong Expert Workstation of Yunnan Province, Kunming 650200, Yunnan, China.
Sheng Wu Gong Cheng Xue Bao. 2025 Feb 25;41(2):574-587. doi: 10.13345/j.cjb.240495.
Ergothioneine is a natural antioxidant known for its potent anti-inflammatory and antioxidative properties. It has been applied in various sectors such as food, cosmetics, and pharmaceuticals. Edible fungi, both wild and cultivated, stand as the primary natural sources capable of synthesizing ergothioneine. This paper reviews the research progress in the content, physiological functions, extraction and detection methods, synthetic genes and pathways, mycelium fermentation, and engineering strain construction for ergothioneine production. The aim is to provide a comprehensive reference for advancing the research and industrial development related to ergothioneine in edible fungi.
麦角硫因是一种天然抗氧化剂,以其强大的抗炎和抗氧化特性而闻名。它已被应用于食品、化妆品和制药等各个领域。野生和栽培的食用菌是能够合成麦角硫因的主要天然来源。本文综述了食用菌中麦角硫因的含量、生理功能、提取和检测方法、合成基因和途径、菌丝体发酵以及工程菌株构建等方面的研究进展。目的是为推进食用菌中麦角硫因的研究和产业发展提供全面的参考。