Ryan Charles W, Rao Rajesh C
Department of Ophthalmology and Visual Science, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, United States.
Medical Scientist Training Program, United States.
IDCases. 2025 Jan 30;39:e02173. doi: 10.1016/j.idcr.2025.e02173. eCollection 2025.
A previously healthy 18-year-old female presented with bilateral cecocentral scotomas two-days after onset of confirmed Influenza A infection, consistent with a post-viral acute macular neuroretinopathy (AMN). Fundoscopy revealed bilateral small petaloid lightening in the nasal macula, and optical coherence tomography revealed thinning of the interdigitation zone, ellipsoid zone, and outer nuclear layer bilaterally. Scotomas and associated imaging findings showed partial improvement in the weeks following diagnosis. This case demonstrates that AMN may be triggered Influenza A infection, and that resulting scotomas and retinal thinning may improve in the weeks following the initial insult.
一名既往健康的18岁女性在确诊甲型流感感染发病两天后出现双侧中心暗点,符合病毒感染后急性黄斑神经视网膜病变(AMN)。眼底检查发现双侧鼻侧黄斑有小花瓣状变淡,光学相干断层扫描显示双侧指状交叉区、椭圆体带和外核层变薄。暗点及相关影像学表现诊断后数周有部分改善。该病例表明AMN可能由甲型流感感染引发,且初始损伤后数周内产生的暗点和视网膜变薄可能改善。