• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

P/J小鼠伤口修复中巨噬细胞功能缺陷

Defective macrophage function in wound repair of P/J mice.

作者信息

Kenyon A J, Douglas D M, Hamilton S G

出版信息

Lab Anim Sci. 1985 Apr;35(2):150-2.

PMID:3999697
Abstract

The strength of healing full-thickness incised dermal wounds in P/J mice was less than that of CD-1 mice although the strength of intact skin was similar for each strain. Five days after surgery, P/J mice had wounds with tensile strengths of 65 +/- 18g while CD-1 mice had wounds with strengths of 85 +/- 15g. The wound breaking strength of P/J mice was restored to normal values (86 +/- 18g) by administering glucan. The consequence of defective monocytes in wound repair is discussed in reference to P/J mice.

摘要

尽管P/J小鼠和CD-1小鼠的完整皮肤强度相似,但P/J小鼠全层切开皮肤伤口的愈合强度低于CD-1小鼠。术后五天,P/J小鼠伤口的抗张强度为65±18克,而CD-1小鼠伤口的强度为85±15克。通过给予葡聚糖,P/J小鼠伤口的抗裂强度恢复到正常值(86±18克)。结合P/J小鼠讨论了单核细胞缺陷在伤口修复中的后果。

相似文献

1
Defective macrophage function in wound repair of P/J mice.P/J小鼠伤口修复中巨噬细胞功能缺陷
Lab Anim Sci. 1985 Apr;35(2):150-2.
2
Modulation of early cellular events in wound healing in mice.
Am J Vet Res. 1983 Feb;44(2):340-3.
3
Effect of macrophage stimulation on collagen biosynthesis in the healing wound.巨噬细胞刺激对愈合伤口中胶原蛋白生物合成的影响。
Am Surg. 1997 Feb;63(2):125-31.
4
Delayed wound healing in mice associated with viral alteration of macrophages.小鼠伤口愈合延迟与巨噬细胞的病毒改变有关。
Am J Vet Res. 1983 Apr;44(4):652-6.
5
Effect of enhanced macrophage function on early wound healing.增强巨噬细胞功能对早期伤口愈合的影响。
Surgery. 1988 Aug;104(2):224-30.
6
830-nm irradiation increases the wound tensile strength in a diabetic murine model.830纳米照射可提高糖尿病小鼠模型的伤口抗张强度。
Lasers Surg Med. 2001;28(3):220-6. doi: 10.1002/lsm.1042.
7
Delayed wound healing in Mac-1-deficient mice is associated with normal monocyte recruitment.Mac-1缺陷小鼠伤口愈合延迟与正常单核细胞募集有关。
Wound Repair Regen. 2007 Jul-Aug;15(4):566-71. doi: 10.1111/j.1524-475X.2007.00264.x.
8
RGTA OTR 4120, a heparan sulfate proteoglycan mimetic, increases wound breaking strength and vasodilatory capability in healing rat full-thickness excisional wounds.RGTA OTR 4120,一种硫酸乙酰肝素蛋白聚糖模拟物,可提高愈合中的大鼠全层切除伤口的抗张强度和血管舒张能力。
Wound Repair Regen. 2008 Mar-Apr;16(2):294-9. doi: 10.1111/j.1524-475X.2008.00368.x.
9
Macrophage colony-stimulating factor accelerates wound healing and upregulates TGF-beta1 mRNA levels through tissue macrophages.巨噬细胞集落刺激因子通过组织巨噬细胞加速伤口愈合并上调转化生长因子-β1 mRNA 水平。
J Surg Res. 1997 Oct;72(2):162-9. doi: 10.1006/jsre.1997.5178.
10
Skin flap closure by dermal laser soldering: a wound healing model for sutureless hypospadias repair.通过真皮激光焊接进行皮瓣闭合:一种用于无缝合尿道下裂修复的伤口愈合模型。
Urology. 1997 Aug;50(2):263-72. doi: 10.1016/S0090-4295(97)00278-1.