Banchelli G, Raimondi L, Ignesti G, Pirisino R, Buffoni F
Med Biol. 1985;63(1):34-9.
The longitudinal smooth muscle of guinea pig ileum contains three different types of oxidative deaminating enzymes: monoamine oxidase types A and B, diamine oxidase and a soluble clorgyline-deprenyl-resistant benzylamine oxidase. These enzymes have different subcellular locations. The longitudinal smooth muscle of guinea pig ileum oxidatively deaminates beta-phenylethylamine at a much higher rate than benzylamine. beta-Phenylethylamine is a good substrate for monoamine oxidase type B but also for the soluble clorgyline-deprenyl-resistant benzylamine oxidase. On the other hand, benzylamine is oxidised by mitochondrial monoamine oxidase, by the clorgyline-deprenyl-resistant enzyme and by diamine oxidase.
A型和B型单胺氧化酶、二胺氧化酶以及一种可溶的、对氯吉兰 - 丙炔苯丙胺耐药的苄胺氧化酶。这些酶具有不同的亚细胞定位。豚鼠回肠的纵行平滑肌氧化脱氨基β-苯乙胺的速率比苄胺高得多。β-苯乙胺是B型单胺氧化酶的良好底物，也是可溶的、对氯吉兰 - 丙炔苯丙胺耐药的苄胺氧化酶的良好底物。另一方面，苄胺可被线粒体单胺氧化酶、对氯吉兰 - 丙炔苯丙胺耐药的酶以及二胺氧化酶氧化。
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