No information is available on the use of axatilimab during breastfeeding. Because axatilimab is a large protein molecule with a molecular weight of about 150,000 Da, the amount in milk is likely to be very low.[1] It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal.[2] The manufacturer recommends that breastfeeding be discontinued during therapy and for 30 days after the last dose.
关于在母乳喂养期间使用阿沙替利单抗的信息尚无可用资料。由于阿沙替利单抗是一种分子量约为150,000道尔顿的大蛋白质分子,其在乳汁中的含量可能非常低。[1]它也可能在婴儿胃肠道中被部分破坏,婴儿的吸收可能微乎其微。[2]制造商建议在治疗期间及最后一剂后30天内停止母乳喂养。