Carbonari Alice, Di Bello Antonio, Lillo Edoardo, Caprio Francesco, Burgio Matteo, Cicirelli Vincenzo, Sciorsci Raffaele Luigi, Rizzo Annalisa
Department of Veterinary Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Vet Med Sci. 2025 Mar;11(2):e70095. doi: 10.1002/vms3.70095.
The study aimed to assess perioperative pain in cats subjected to ovariectomy, performed with a midline or flank approach, receiving a lidocaine splash on each ovarian pedicle.
Eighty female cats were divided into two groups: flank group (F), made up of 40 subjects ovariectomised using the flank approach, and the midline group (M), which consisted of 40 subjects using the midline approach. Each group was divided into two subgroups: the local anaesthesia group (L), consisting of 20 cats belonging to group F (LF) and 20 cats belonging to group M (LM), which received a splash of lidocaine (4 mg/kg) diluted in 0.5 mL/kg of saline solution on the ovarian pedicles before their ligation, and the control group (C), consisting of 20 cats belonging to group F (CF) and 20 cats belonging to group M (CM), which received the same splash using saline solution. Heart rate, respiratory rate and systolic blood pressure were monitored to assess intraoperative nociception response. An operator assigned postoperative pain scores following the Glasgow scale revised composite measure pain scale feline.
Intraoperative HR and SBP and postoperative pain scores were higher in the control groups. The number of patients requiring rescue analgesia was higher in the control groups. In the midline approach, HR and SBP increased significantly during exteriorisation of both ovaries, while in the flank approach, this occurred predominantly during exteriorisation of the second ovary.
Concurred use of local and systemic analgesia in cats undergoing flank or midline ovariectomy may reduce intraoperative nociception and postoperative pain and reduce the need for rescue analgesia.
本研究旨在评估采用中线或侧腹入路进行卵巢切除术，并在每个卵巢蒂上喷洒利多卡因的猫的围手术期疼痛情况。
80只雌性猫被分为两组：侧腹组（F），由40只采用侧腹入路进行卵巢切除的猫组成；中线组（M），由40只采用中线入路的猫组成。每组又分为两个亚组：局部麻醉组（L），由20只属于F组的猫（LF）和20只属于M组的猫（LM）组成，在结扎卵巢蒂之前，它们在卵巢蒂上接受了用0.5 mL/kg盐溶液稀释的利多卡因（4 mg/kg）喷洒；对照组（C），由20只属于F组的猫（CF）和20只属于M组的猫（CM）组成，它们接受了相同的盐溶液喷洒。监测心率、呼吸频率和收缩压以评估术中伤害感受反应。一名操作人员按照格拉斯哥修订复合测量疼痛量表（猫用）对术后疼痛进行评分。
对照组的术中心率和收缩压以及术后疼痛评分更高。对照组中需要急救镇痛的动物数量更多。在中线入路中，两侧卵巢娩出时心率和收缩压显著升高，而在侧腹入路中，这主要发生在第二个卵巢娩出时。
在接受侧腹或中线卵巢切除术的猫中联合使用局部和全身镇痛可能会减少术中伤害感受和术后疼痛，并减少对急救镇痛的需求。
