Lalchand Punita, Ashley Didier-Deschamps, Pan Xue
Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON, M1C 1A4 Canada; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, M5S 3G5 Canada.
Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON, M1C 1A4 Canada; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, M5S 3G5 Canada.
Curr Opin Plant Biol. 2025 Apr;84:102697. doi: 10.1016/j.pbi.2025.102697. Epub 2025 Feb 24.
Biomolecular condensates, often formed through liquid-liquid phase separation (LLPS), are increasingly recognized as a critical mechanism for cellular compartmentalization across diverse biological systems. Although traditionally considered membrane-less entities, recent discoveries highlight their dynamic interactions with membranes, where they regulate various processes, including signal transduction. Signaling lipids are observed in condensates. Despite these advancements, our understanding of such condensates in plant biology remains limited. This review highlights recent studies involving membrane-associated condensates in plants, focusing particularly on their interactions with the plasma membrane (PM) and their potential roles in PM-based signaling.
生物分子凝聚物通常通过液-液相分离（LLPS）形成，越来越被认为是跨多种生物系统进行细胞区室化的关键机制。尽管传统上被认为是无膜实体，但最近的发现突出了它们与膜的动态相互作用，在膜上它们调节包括信号转导在内的各种过程。在凝聚物中观察到了信号脂质。尽管有这些进展，但我们对植物生物学中此类凝聚物的理解仍然有限。本综述重点介绍了最近关于植物中与膜相关的凝聚物的研究，特别关注它们与质膜（PM）的相互作用及其在基于PM的信号传导中的潜在作用。
