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气态微栓子:来源、成因及临床考量

Gaseous microemboli: sources, causes, and clinical considerations.

作者信息

Kurusz M

出版信息

Med Instrum. 1985 Mar-Apr;19(2):73-6.

PMID:4000011
Abstract

Patients undergoing open-heart surgery are exposed to gaseous microemboli (GME) from several sources, including bubble oxygenators, which are used in a majority of cases for cardiopulmonary bypass. If present in large quantities, GME can reduce blood flow and delivery of oxygen to tissues and may be responsible, in part, for some of the complications that commonly follow cardiopulmonary bypass. Gaseous microemboli are defined, and the causes of this phenomenon are examined. The literature from the last 30 years on this topic is also reviewed, and measures for reducing GME during cardiopulmonary bypass are recommended. Current considerations for users of cardiopulmonary bypass systems are discussed, and five unanswered questions are raised in the conclusion.

摘要

接受心脏直视手术的患者会接触到来自多种源头的气态微栓子(GME),包括鼓泡式氧合器,在大多数体外循环病例中都会用到鼓泡式氧合器。如果大量存在,气态微栓子会减少血液流动以及向组织输送氧气,并且可能部分导致体外循环后常见的一些并发症。文中对气态微栓子进行了定义,并研究了这一现象的成因。还回顾了过去30年关于该主题的文献,并推荐了在体外循环期间减少气态微栓子的措施。讨论了体外循环系统使用者当前需要考虑的问题,并在结论中提出了五个未解决的问题。

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