Wu Yue, Wang Yiting, Wang Haijun, Jia Shaowei, Ao Yingfang, Gong Xi, Liu Zhenlong
Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing 100191, China.
Beijing Key Laboratory of Sports Injuries, Beijing Municipal Science and Technology Commission, Beijing 100191, China.
Bioengineering (Basel). 2025 Feb 8;12(2):165. doi: 10.3390/bioengineering12020165.
Anterior cruciate ligament (ACL) rupture and patellar dislocation (PD) are common knee injuries. Dual-energy X-ray absorptiometry (DXA) and computed tomography (CT) are widely used clinical diagnostic tools. The aim was to investigate the characteristics of knee bone mineral density (BMD) in patients with ACL rupture and PD and to explore the relationship between BMD and Hounsfield unit (HU) values. This prospective cross-sectional study included 32 ACL rupture and 32 PD patients assessed via DXA and CT. BMD and CT measurements were taken from regions of interest in the femoral and tibial condyles. Statistical analyses included t-tests and mixed-effects models. The results showed that BMD in the PD group was significantly lower than in the ACL group ( < 0.05). The HU values of cortical bone in the femur and tibia differed significantly between the ACL group and the PD group ( < 0.05). The BMD of the femur and tibia showed significant correlations with the HU values of cancellous bone and cortical bone ( < 0.05). The conclusion was that PD patients had lower BMD and HU values in the femur and tibia compared to patients with ACL ruptures, particularly in the cortical bone of the tibia, and there was a strong correlation between HU value and BMD.
前交叉韧带(ACL)断裂和髌骨脱位(PD)是常见的膝关节损伤。双能X线吸收法(DXA)和计算机断层扫描(CT)是广泛使用的临床诊断工具。目的是研究ACL断裂和PD患者膝关节骨密度(BMD)的特征,并探讨BMD与亨氏单位(HU)值之间的关系。这项前瞻性横断面研究纳入了32例ACL断裂患者和32例PD患者,通过DXA和CT进行评估。从股骨和胫骨髁的感兴趣区域进行BMD和CT测量。统计分析包括t检验和混合效应模型。结果显示,PD组的BMD显著低于ACL组(<0.05)。ACL组和PD组之间股骨和胫骨皮质骨的HU值存在显著差异(<0.05)。股骨和胫骨的BMD与松质骨和皮质骨的HU值呈显著相关(<0.05)。结论是,与ACL断裂患者相比,PD患者股骨和胫骨的BMD和HU值较低,尤其是胫骨皮质骨,且HU值与BMD之间存在强相关性。