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使用法国国家医疗信息系统(PMSI)数据库评估法国肺癌手术的结果质量

Evaluation of the Quality of Results of Lung Cancer Surgery in France Using the PMSI National Database.

作者信息

Bernard Alain, Cottenet Jonathan, Quantin Catherine

机构信息

Department of Thoracic and Cardiovascular Surgery, University Hospital, 21000 Dijon, France.

Department of Biostatistics and Bioinformatics, University Hospital, 21000 Dijon, France.

出版信息

Cancers (Basel). 2025 Feb 11;17(4):617. doi: 10.3390/cancers17040617.

Abstract

. Given the complexity of lung cancer surgery, this study aims to provide an overview of hospitals authorised to perform lung cancer surgery in France, and to assess their performance focusing on severe post-operative complications and 30-day in-hospital mortality based on the Clavien-Dindo classification (grade > 2). . We included all patients (n = 64,304) who underwent pulmonary resection for lung cancer from the French hospital database (2019-2023). To quantify variations within regions, we used the ratio of the 90th to the 10th decile of the standardised outcome rate of the hospitals. We used a hierarchical logistic regression model to estimate the adjusted odds ratio (aOR) according to the number of annual procedures. We then used the results of this modelling to see how the standardised rate estimate might evolve after simulating a new organisation of hospitals authorised to perform this surgery. . A total of 18,151 patients (28%) had severe complications (Clavien-Dindo > 2). Compared to hospital performing less than 100 procedures/year, the risk of severe complications was significantly reduced for hospitals performing between 101 and 250 procedures/year (aOR = 0.83 [0.77-0.89]) and more than 250 procedures/year (aOR = 0.85 [0.77-0.93]). A simulation of hospital reorganisation, using 100 procedures/year as the threshold value, showed that 477 severe complications could have been prevented over the period. . This study shows inequalities in performance indicators between hospitals in each French region. The influence of the volume of activity raises questions about the need to restructure the offer of care for complex surgeries, such as lung cancer surgery.

摘要

鉴于肺癌手术的复杂性,本研究旨在概述法国获准开展肺癌手术的医院,并根据Clavien-Dindo分类(2级以上)评估其在严重术后并发症和30天院内死亡率方面的表现。我们纳入了法国医院数据库(2019 - 2023年)中所有接受肺癌肺切除术的患者(n = 64,304)。为了量化各地区内的差异,我们使用了医院标准化结局率第90百分位数与第10百分位数的比值。我们使用分层逻辑回归模型根据年度手术数量估计调整后的优势比(aOR)。然后,我们利用该模型的结果来观察在模拟一种新的获准开展该手术的医院组织形式后,标准化率估计值可能会如何变化。共有18,151名患者(28%)出现严重并发症(Clavien-Dindo > 2)。与每年手术量少于100例的医院相比,每年手术量在101至250例之间的医院严重并发症风险显著降低(aOR = 0.83 [0.77 - 0.89]),每年手术量超过250例的医院严重并发症风险也显著降低(aOR = 0.85 [0.77 - 0.93])。以每年100例手术作为阈值进行医院重组模拟显示,在此期间可预防477例严重并发症。本研究显示了法国各地区医院在绩效指标方面存在不平等。手术量的影响引发了对于是否需要重组复杂手术(如肺癌手术)护理服务的质疑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a65/11852714/a56482e343d1/cancers-17-00617-g001.jpg

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