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早期婴儿孤独症的脑组解剖学观察

Histoanatomic observations of the brain in early infantile autism.

作者信息

Bauman M, Kemper T L

出版信息

Neurology. 1985 Jun;35(6):866-74. doi: 10.1212/wnl.35.6.866.

DOI:10.1212/wnl.35.6.866
PMID:4000488
Abstract

Early infantile autism is a behaviorally defined syndrome that is often associated with abnormalities on neurologic examination and seizures. We report on the brain of a 29-year-old autistic man as compared with that of an age- and sex-matched normal control, using gapless sections of whole brain. Abnormalities were found in the hippocampus, subiculum, entorhinal cortex, septal nuclei, mamillary body, selected nuclei of the amygdala, neocerebellar cortex, roof nuclei of the cerebellum, and inferior olivary nucleus.

摘要

早期婴儿自闭症是一种行为学定义的综合征,常与神经系统检查异常和癫痫发作相关。我们报告了一名29岁自闭症男性的大脑,并与年龄和性别匹配的正常对照者的大脑进行比较,采用了全脑无缝切片。在海马体、下托、内嗅皮质、隔核、乳头体、杏仁核的选定核团、新小脑皮质、小脑顶核和下橄榄核中发现了异常。

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