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儿童骶管阻滞时使用超声评估两种不同剂量局部麻醉药的颅内扩散情况。

Assessment of Cranial Spread of Two Different Volumes of Local Anesthetics Using Ultrasound during Caudal Blockade in Children.

作者信息

Thaleppady Megha, John Nithin, Kulkarni Malavika, Rani K Rama, Satish Aparna, Shenoy Laxmi

机构信息

Department of Anaesthesia, Kasturba Medical College, Mangaluru, Manipal Academy of Higher Education, Karnataka, India.

Fellow in Cardiac Anaesthesia, Lisie Hospital, Kochi, Kerala, India.

出版信息

Ann Afr Med. 2025 Apr 1;24(2):244-248. doi: 10.4103/aam.aam_112_24. Epub 2025 Feb 25.

Abstract

BACKGROUND AND AIMS

Single-shot caudal anesthesia is the most commonly used regional anesthesia technique in children with broad spectrum of indications. Although several studies have been in relation to caudal anesthesia the issue of volume of local anesthetics and its cranial spread has always been a matter of debate with discrepancies noted between clinical assessment and radiographic spread of the drug. The aim of the present study was to evaluate the cranial spread of two volumes of caudally administered local anesthetics in pediatric patients by means of real-time ultrasound.

MATERIALS AND METHODS

Fifty children of 1-6 years of age belonging to American Society of Anesthesiologists status I/II scheduled for infraumbilical surgeries were administered general anesthesia followed by ultrasound guided caudal anesthesia with 0.25% levobupivacaine, either 1 ml/kg or 0.75 ml/kg with 25 children in each group. Real-time placement of the drug and its maximum cranial spread with respect to T12 vertebrae was noted using ultrasound. Hemodynamic parameters on surgical incision was noted among the groups. Frequencies are presented with descriptive statistics and t -test is used to study difference between the two groups.

RESULTS

It was noted that the group receiving 0.75 ml/kg of drug had the drug spread between the L2 and L3 vertebral level and the group receiving 1 ml/kg had spread between L1 and L2. There was a positive correlation between dose of drug and distance from T12 vertebra with 1 ml/kg of the drug having a mean of 3.25 ± 1.07 cm whereas 0.75 ml/kg had a mean of 4.44 ± 0.87 cm ( P = 0.0001). Patient demographics and hemodynamic parameters on incision were comparable among the groups.

CONCLUSION

This study showed that there was a positive correlation between volume of local anesthetic injected in caudal space and its cranial spread with respect to distance from T12 however on comparison between vertebral levels the maximum deposition of local anesthetic was between L1 and L2 for 1 ml/kg and between L2 and L3 for 0.75 ml/kg, respectively.

摘要

背景与目的

单次骶管麻醉是儿童中最常用的区域麻醉技术,适应证广泛。尽管已有多项关于骶管麻醉的研究,但局部麻醉药的用量及其向头端扩散的问题一直存在争议,临床评估与药物的影像学扩散情况之间存在差异。本研究的目的是通过实时超声评估两不同剂量的骶管注射局部麻醉药在儿科患者中的头端扩散情况。

材料与方法

五十名年龄在1至6岁、美国麻醉医师协会分级为I/II级、计划接受脐下手术的儿童,先接受全身麻醉,随后在超声引导下用0.25%左旋布比卡因进行骶管麻醉,每组25名儿童,分别给予1 ml/kg或0.75 ml/kg的药物。使用超声记录药物的实时注射位置及其相对于T12椎体的最大头端扩散情况。记录各组手术切口时的血流动力学参数。频率采用描述性统计呈现,t检验用于研究两组之间的差异。

结果

结果显示,接受0.75 ml/kg药物的组,药物扩散至L2和L3椎体水平之间;接受1 ml/kg药物的组,药物扩散至L1和L2之间。药物剂量与距T12椎体的距离呈正相关,1 ml/kg药物的平均距离为3.25±1.07 cm,而0.75 ml/kg药物的平均距离为4.44±0.87 cm(P = 0.0001)。各组患者的人口统计学特征和切口时的血流动力学参数具有可比性。

结论

本研究表明,骶管间隙注射的局部麻醉药用量与其相对于T12的头端扩散呈正相关,但在椎体水平比较时,1 ml/kg局部麻醉药的最大沉积分别在L1和L2之间,0.75 ml/kg局部麻醉药的最大沉积分别在L2和L3之间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ee5/12103144/39e508b788b1/AAM-24-244-g001.jpg

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